Gene Symbol | CXCL17 |
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Entrez Gene | 284340 |
Alt Symbol | DMC, Dcip1, UNQ473, VCC-1, VCC1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 17 |
Other Description | C-X-C motif chemokine 17|VEGF co-regulated chemokine 1|VEGF coregulated chemokine 1|dendritic cell and monocyte chemokine-like protein |
Swissprots | Q6UXB2 A8KAC0 |
Accessions | Q6UXB2 AK292985 BAF85674 AY358433 AAQ88799 AY598464 AAU04875 BC093946 AAH93946 BC112095 AAI12096 NM_198477 NP_940879 |
Function | Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774, ECO:0000269|PubMed:17307946}. |
Subcellular Location | Secreted. |
Tissue Specificity | Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up- regulation. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774}. |
VCC-1 CRISPR/Cas9 KO Plasmid (h) - sc-416268 from Santa Cruz Biotechnology
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VCC-1 HDR Plasmid (h) - sc-416268-HDR from Santa Cruz Biotechnology
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VCC-1 Double Nickase Plasmid (h) - sc-416268-NIC from Santa Cruz Biotechnology
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VCC-1 Double Nickase Plasmid (h2) - sc-416268-NIC-2 from Santa Cruz Biotechnology
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VCC-1 CRISPR Activation Plasmid (h) - sc-416268-ACT from Santa Cruz Biotechnology
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VCC-1 CRISPR Activation Plasmid (h2) - sc-416268-ACT-2 from Santa Cruz Biotechnology
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VCC-1 Lentiviral Activation Particles (h) - sc-416268-LAC from Santa Cruz Biotechnology
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VCC-1 Lentiviral Activation Particles (h2) - sc-416268-LAC-2 from Santa Cruz Biotechnology
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VCC-1 siRNA (h) - sc-97107 from Santa Cruz Biotechnology
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VCC-1 shRNA Plasmid (h) - sc-97107-SH from Santa Cruz Biotechnology
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VCC-1 shRNA (h) Lentiviral Particles - sc-97107-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU129831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6803 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6803 from Sigma-Aldrich
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CXCL17 siRNA (Human) - CRJ7000 from Cohesion Biosciences
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CXCL17 - MBS8220974 from MyBioSource
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shRNA set against Human CXCL17 (NM_198477.1) - SHH272189 from Creative biogene
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Human CXCL17 siRNA - orb277501 from Biorbyt
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CXCL17 shRNA Plasmid (Human) - CHJ7000 from Cohesion Biosciences
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CXCL17 miRNA 3'UTR clone - MiUTR1H-11021 from Creative biogene
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