CXCL17

Gene Symbol	CXCL17
Entrez Gene	284340
Alt Symbol	DMC, Dcip1, UNQ473, VCC-1, VCC1
Species	Human
Gene Type	protein-coding
Description	chemokine (C-X-C motif) ligand 17
Other Description	C-X-C motif chemokine 17\|VEGF co-regulated chemokine 1\|VEGF coregulated chemokine 1\|dendritic cell and monocyte chemokine-like protein
Swissprots	Q6UXB2 A8KAC0
Accessions	Q6UXB2 AK292985 BAF85674 AY358433 AAQ88799 AY598464 AAU04875 BC093946 AAH93946 BC112095 AAI12096 NM_198477 NP_940879
Function	Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269\|PubMed:16455961, ECO:0000269\|PubMed:16989774, ECO:0000269\|PubMed:17307946}.
Subcellular Location	Secreted.
Tissue Specificity	Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up- regulation. {ECO:0000269\|PubMed:16455961, ECO:0000269\|PubMed:16989774}.

VCC-1 (B-3) - sc-398842 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

VCC-1 (B-3): sc-398842. Western blot analysis of VCC-1 expression in human lung tissue extract.

VCC-1 (G-13) - sc-169779 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

VCC-1 (G-13): sc-169779. Western blot analysis of VCC-1 expression in human small intestine tissue extract.

VCC-1 (W-12) - sc-169783 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

VCC-1 (H-43) - sc-292019 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

VCC-1 (H-43): sc-292019. Western blot analysis of VCC-1 expression in WI-38 whole cell lysate.

Anti-VCC-1 / CXCL17 Antibody (aa24-119) - LS-C125470 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-VCC-1 / CXCL17 Antibody (aa31-119) - LS-C125471 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal

Anti-VCC-1 / CXCL17 Antibody (Biotin) - LS-C125472 from LifeSpan Bioscience

Prices	$650.00
Sizes	50 µg
Host	Sheep
Clonality	Polyclonal

Anti-VCC-1 / CXCL17 Antibody (aa24-119, Biotin) - LS-C298126 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VCC-1 / CXCL17 Antibody (aa24-119, FITC) - LS-C302237 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VCC-1 / CXCL17 Antibody (aa24-119) - LS-C296977 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of recombinant VCC-1 / CXCL17.

CXCL17/VCC-1 Antibody (422208) [Unconjugated] - MAB4207 from Novus Biologicals

Prices	$249.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	422208

Intracellular Staining by Flow Cytometry CXCL17/VCC-1 Antibody (422208) [Unconjugated]

CXCL17/VCC-1 Antibody - AF4207 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

Human CXCL17/VCC-1 Antibody - MAB4207 from R&D Systems

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clone	422208

Detection of CXCL17/VCC-1 in A549 Human Cell Line by Flow Cytometry. A549 human lung carcinoma cell line was stained with Mouse Anti-Human CXCL17/VCC-1 Monoclonal Antibody (Catalog # MAB4207, filled histogram) or isotype control antibody (Catalog # MAB0041 , open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab') 2 Secondary Antibody (Catalog # F0101B ). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

Human CXCL17/VCC-1 MAb (Clone 422208), Mouse IgG2B - MAB4207-SP from R&D Systems

Host	Mouse
Clonality	Monoclonal
Clone	422208

Mouse CXCL17/VCC-1 Antibody - AF4270 from R&D Systems

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep

Mouse CXCL17/VCC-1 Affinity Purified Polyclonal Ab, Sheep IgG - AF4270-SP from R&D Systems

Host	Sheep
Clonality	Polyclonal

Mouse CXCL17/VCC-1 Antibody - MAB4270 from R&D Systems

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Rat
Clone	510614

Detection of Mouse CXCL17 by Western Blot. Western blot shows lysates of mouse lung tissue. PVDF membrane was probed with 2 µg/mL of Rat Anti-Mouse CXCL17 Monoclonal Antibody (Catalog # MAB4270) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005 ). A specific band was detected for CXCL17 at approximately 11 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 (with 3% BSA instead of 5% milk in the Antibody Solution) .

Mouse CXCL17/VCC-1 MAb (Clone 510614), Rat IgG2B - MAB4270-SP from R&D Systems

Host	Rat
Clonality	Monoclonal
Clone	510614

Human CXCL17/VCC-1 Antibody - AF4207 from R&D Systems

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep

Human CXCL17/VCC-1 Affinity Purified Polyclonal Ab, Sheep IgG - AF4207-SP from R&D Systems

Host	Sheep
Clonality	Polyclonal

Mouse CXCL17/VCC-1 Biotinylated Antibody - BAF4270 from R&D Systems

Prices	$390.00
Sizes	50 µg
Host	Sheep

Anti -DMC (Dendritic cell and Monocyte Chemokine-like Protein, VEGF Co-regulated Chemokine1, VCC1) - D8074-90B from USBiological Life Science

Host	Mouse
Clonality	Monoclonal
Clone	7H252

VCC1 Antibody - abx103076 from Abbexa

Host	Rabbit
Clonality	Polyclonal

CXCL17 antibody - 18108-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 18108-1-AP( CXCL17 Antibody) at dilution of 1:50 (under 10x lens)

Recombinant Human CXCL17 (VCC-1) (carrier-free) - 585302 from Biolegend

Prices	$155.00, $285.00, $615.00, $1,785.00
Sizes	10 µg, 25 µg, 100 µg, 500 µg

Bactericidal activity of human CXCL17 against E.coli.

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