| Gene Symbol | Leprot |
|---|---|
| Entrez Gene | 56766 |
| Alt Symbol | Ob-Rgrp, Obrgrp |
| Species | Rat |
| Gene Type | protein-coding |
| Description | leptin receptor overlapping transcript |
| Other Description | OB-R gene-related protein|OB-receptor gene related protein (OB-RGRP)|endospanin-1|leptin receptor gene-related protein |
| Swissprots | Q9JLS8 |
| Accessions | CBX85067 EDL97833 Q9JLS8 AF139209 AAF63411 BC062003 AAH62003 FQ225517 NM_020099 NP_064484 |
| Function | Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin (By similarity). Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. {ECO:0000250, ECO:0000269|PubMed:19907080}. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}. |
CompoZr® Knockout ZFN Kit - CKOZFN56111 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND56111 from Sigma-Aldrich
|
||||||||
LEPROT siRNA (Rat) - CRR1524 from Cohesion Biosciences
|
||||||||
shRNA set against Rat Leprot(NM_020099.2) - SHH146711 from Creative biogene
|
||||||||
Rat LEPROT siRNA - orb296373 from Biorbyt
|
||||||||
LEPROT shRNA Plasmid (Rat) - CHR1524 from Cohesion Biosciences
|
||||||||
LEPROT miRNA 3'UTR clone - MiUTR1R-02986 from Creative biogene
|