INPP5E

Gene Symbol INPP5E
Entrez Gene 56623
Alt Symbol CORS1, CPD4, JBTS1, MORMS, PPI5PIV
Species Human
Gene Type protein-coding
Description inositol polyphosphate-5-phosphatase, 72 kDa
Other Description 72 kDa inositol polyphosphate 5-phosphatase|phosphatidylinositol (4,5) bisphosphate 5-phosphatase|phosphatidylinositol 4,5-bisphosphate 5-phosphatase|phosphatidylinositol polyphosphate 5-phosphatase type IV|phosphatidylinositol-4,5-bisphosphate 5-phosphatase
Swissprots Q6PIV5 Q9NRR6 Q15734
Accessions EAW88233 EAW88234 EAW88235 Q9NRR6 AF187891 AAF81404 AL832846 BC028032 AAH28032 BC110356 AAI10357 BE044535 BE314630 U45974 AAB03215 XM_005266094 XP_005266151 XR_929828 NM_019892 NP_063945
Function Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2, and phosphatidylinositol 4,5- bisphosphate to phosphatidylinositol 4-phosphate. Specific for lipid substrates, inactive towards water soluble inositol phosphates. {ECO:0000269|PubMed:10764818}.
Subcellular Location Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:19668215, ECO:0000269|PubMed:19668216, ECO:0000269|PubMed:24166846}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q9JII1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9JII1}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9JII1}. Cell membrane {ECO:0000250|UniProtKB:Q9WVR1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9WVR1}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVR1}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9WVR1}. Cytoplasm {ECO:0000250|UniProtKB:Q9WVR1}. Note=Peripheral membrane protein associated with Golgi stacks. {ECO:0000250|UniProtKB:Q9JII1}.
Tissue Specificity Detected in brain, heart, pancreas, testis and spleen. {ECO:0000269|PubMed:10764818}.
Top Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system

INPP5E (S-13) - sc-161086 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
INPP5E (S-13): sc-161086. Western blot analysis of INPP5E expression in mouse testis tissue extract.

Anti-INPP5E antibody - ab191520 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-INPP5E antibody (ab191520)Lane 1 : HEK293T whole cell lysateLane 2 : sp2/0 whole cell lysateLane 3 : H9C2 whole cell lysate

Anti-INPP5E antibody - ab69696 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-INPP5E antibody (ab69696) at 1/500 dilutionLane 1 : INPP5E transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-INPP5E Antibody - LS-C308496 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-INPP5E Antibody - LS-C340934 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INPP5E Antibody - LS-C333645 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using INPP5E antibody.

INPP5E Antibody - NB110-55574 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: INPP5E Antibody [NB110-55574] - Analysis of anti-INPP5J / PIB5PA antibody with human kidney.

INPP5E Antibody - H00056623-B01 from Novus Biologicals

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: INPP5E Antibody [H00056623-B01] - Analysis of INPP5E expression in transfected 293T cell line. Lane 1: INPP5E transfected lysate (70.84 KDa). Lane 2: Non-transfected lysate.

INPP5E Antibody - H00056623-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: INPP5E Antibody [H00056623-B01P] - Analysis of INPP5E expression in transfected 293T cell line by INPP5E polyclonal antibody. Lane 1: INPP5E transfected lysate(70.84 KDa). Lane 2: Non-transfected lysate.

Anti-INPP5E antibody produced in rabbit - SAB1412856 from Sigma-Aldrich

Prices $391.50
Sizes 100 µg
Host Rabbit
<B>Immunoblotting</B><BR/>Anti-INPP5E:<B>Cat. No. SAB1412856</B>: Antibody concentration: 0.1–5 μg/mL. Immunofluorescence band of ~70.2 kDa using INPP5E transfected 293T lysate.<BR/><B>Lane</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-INPP5E antibody produced in mouse - SAB1407741 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-INPP5E: <B>Cat. No. SAB1407741</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~70.8 kDa using INPP5E transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

INPP5E Polyclonal Antibody - A4863 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using INPP5E antibody.

INPP5E antibody - 70R-17980 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

INPP5E Antibody - abx003688 from Abbexa

Host Rabbit
Clonality Polyclonal

INPP5E Antibody - abx007766 from Abbexa

Host Rabbit
Clonality Polyclonal

INPP5E antibody - 17797-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human testis using 17797-1-AP(INPP5E antibody) at dilution of 1:50 (under 10x lens)

INPP5E antibody - H00056623-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of INPP5E expression in transfected 293T cell line (H00056623-T01) by INPP5E MaxPab polyclonal antibody.Lane 1: INPP5E

INPP5E antibody - H00056623-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of INPP5E expression in transfected 293T cell line (H00056623-T01) by INPP5E MaxPab polyclonal antibody. Lane 1: INPP5E transfected lysate(70.84 KDa). Lane 2: Non-transfected lysate.

INPP5E antibody - H00056623-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-INPP5E, Polyclonal Antibody - 25-A4863 from ARP American Research Products

Prices $419.00, $619.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

INPP5E antibody - STJ26920 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

INPP5E antibody - 17797-1-AP from Proteintech Group

Prices $279.00
Sizes con: 54 μg/150μl
Host Rabbit
Clonality Polyclonal
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 17797-1-AP(INPP5E antibody) at dilution of 1:1000
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