Gene Symbol | KCNV1 |
---|---|
Entrez Gene | 27012 |
Alt Symbol | HNKA, KCNB3, KV2.3, KV8.1 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated modifier subfamily V, member 1 |
Other Description | neuronal potassium channel alpha subunit HNKA|potassium channel Kv8.1|potassium channel, subfamily V, member 1|potassium voltage-gated channel subfamily V member 1|voltage-gated potassium channel subunit Kv8.1 |
Swissprots | Q9UHJ4 Q6PIU1 |
Accessions | BAA92316 BAC85099 EAW91938 Q6PIU1 AF035317 AF167082 AAD48031 AK297393 BAG59833 AK308123 AK313469 BAG36254 BC028739 AAH28739 DQ892413 ABM83339 DQ895627 ABM86553 XM_005250866 XP_005250923 NM_014379 NP_055194 |
Function | Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. {ECO:0000269|PubMed:8670833, ECO:0000269|PubMed:9079713}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:8670833, ECO:0000269|PubMed:9079713}; Multi-pass membrane protein {ECO:0000269|PubMed:8670833, ECO:0000269|PubMed:9079713}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2. |
Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:12383276}. |
Human KCNV1 full length protein - ab162054 from Abcam
|
||||||||||
Human KCNV1 protein fragment - ab162055 from Abcam
|
||||||||||
KCNV1 / Kv8.1 Antibody Blocking Peptide - LS-E7975 from LifeSpan Bioscience
|
||||||||||
Recombinant Human Kv8.1 Protein - H00027012-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human Kv8.1 Protein - H00027012-P01 from Novus Biologicals
|
||||||||||
KCNV1-Antibody-N-term-Blocking-peptide - BP5787a from Abgent, a WuXi AppTec company
|
||||||||||
KCNV1 Blocking Peptide - 33R-1332 from Fitzgerald
|
||||||||||
KCNV1 - H00027012-P01-10 from Acris Antibodies
|
||||||||||
KCNV1 - H00027012-P01-25 from Acris Antibodies
|
||||||||||
KCNV1 - H00027012-Q01-10 from Acris Antibodies
|
||||||||||
KCNV1 - H00027012-Q01-25 from Acris Antibodies
|
||||||||||
KCNV1 fusion protein - Ag14596 from Proteintech Group
|
||||||||||
KCNV1 fusion protein - Ag3376 from Proteintech Group
|
||||||||||
Recombinant Human KCNV1, His-tagged - KCNV1-287H from Creative Biomart
|
||||||||||
KCNV1 Peptide, Human - M34GP08010H from Creative Peptides
|
||||||||||
Potassium voltage-gated channel subfamily V member 1 (KCNV1), Recombinant Protein - MBS7017802 from MyBioSource
|
||||||||||
Potassium voltage-gated channel subfamily V member 1 (KCNV1), Recombinant Protein - MBS7017806 from MyBioSource
|