SLC27A5

Gene Symbol	SLC27A5
Entrez Gene	10998
Alt Symbol	ACSB, ACSVL6, BACS, BAL, FACVL3, FATP-5, FATP5, VLACSR, VLCS-H2, VLCSH2
Species	Human
Gene Type	protein-coding
Description	solute carrier family 27 (fatty acid transporter), member 5
Other Description	BA-CoA ligase|VLACS-related|bile acid-CoA ligase|bile acyl-CoA synthetase|cholate--CoA ligase|fatty acid transport protein 5|fatty-acid-Coenzyme A ligase, very long-chain 3|solute carrier family 27 member 5|very long-chain acyl-CoA synthetase homolog 2|very long-chain acyl-CoA synthetase-related protein
Swissprots	B4DPQ1 Q9Y2P5 B3KVP6
Accessions	EAW72601 Q9Y2P5 AB208931 BAD92168 AF064255 AAD29444 AK026640 AK123036 BAG53858 AK298446 BAG60663 BC146387 AAI46388 BC148807 AAI48808 BX103174 XM_011526363 XP_011524665 XM_011526364 XP_011524666 NM_012254 NP_036386
Function	Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. {ECO:0000269|PubMed:10749848, ECO:0000269|PubMed:11980911}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10479480}; Multi-pass membrane protein {ECO:0000269|PubMed:10479480}.
Tissue Specificity	Predominantly expressed in liver. {ECO:0000269|PubMed:10479480}.
Top Pathways	Primary bile acid biosynthesis, PPAR signaling pathway, Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACSVL6 (C-8) - sc-377374 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

ACSVL6 (A-20) - sc-70169 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ACSVL6 (G-14) - sc-70172 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ACSVL6 (H-46) - sc-135230 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-SLC27A5 antibody - ab74869 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 antibody - ab89008 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-SLC27A5 antibody - ab97884 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC27A5 antibody [4B11C10] - ab166698 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4B11C10

Anti-SLC27A5 antibody [CL0213] - ab154140 from Abcam Prices $443.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone CL0213

Anti-SLC27A5 / BACS Antibody (aa488-690, Biotin) - LS-C297302 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 / BACS Antibody (aa488-690, FITC) - LS-C303103 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 / BACS Antibody (aa611-660) - LS-C107515 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 / BACS Antibody (aa488-690) - LS-C293846 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 / BACS Antibody (aa481-530) - LS-C119783 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC27A5 / BACS Antibody (aa508-570, clone 9C4D1) - LS-C191776 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 9C4D1

Anti-SLC27A5 / BACS Antibody (aa508-570, clone 9C4D1) - LS-C191777 from LifeSpan Bioscience Prices $365.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 9C4D1

Anti-SLC27A5 / BACS Antibody (aa508-570, clone 4B11C10) - LS-C191775 from LifeSpan Bioscience Prices $365.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4B11C10

Anti-SLC27A5 / BACS Antibody (aa508-570, clone 4B11C10) - LS-C191774 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4B11C10

FATP5/SLC27A5 Antibody (4B11C10) - NBP2-37413 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4B11C10

FATP5/SLC27A5 Antibody (9C4D1) - NBP2-37412 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 9C4D1

FATP5/SLC27A5 Antibody - NBP1-89267 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FATP5/SLC27A5 Antibody (CL0213) - NBP2-14788 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone CL0213

FATP5/SLC27A5 Antibody (390917) [Unconjugated] - MAB3897 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 390917

FATP5/SLC27A5 Antibody - H00010998-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

FATP5/SLC27A5 Antibody - H00010998-D01 from Novus Biologicals Prices $399.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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