SLC27A5

Gene Symbol SLC27A5
Entrez Gene 10998
Alt Symbol ACSB, ACSVL6, BACS, BAL, FACVL3, FATP-5, FATP5, VLACSR, VLCS-H2, VLCSH2
Species Human
Gene Type protein-coding
Description solute carrier family 27 (fatty acid transporter), member 5
Other Description BA-CoA ligase|VLACS-related|bile acid-CoA ligase|bile acyl-CoA synthetase|cholate--CoA ligase|fatty acid transport protein 5|fatty-acid-Coenzyme A ligase, very long-chain 3|solute carrier family 27 member 5|very long-chain acyl-CoA synthetase homolog 2|very long-chain acyl-CoA synthetase-related protein
Swissprots B4DPQ1 Q9Y2P5 B3KVP6
Accessions EAW72601 Q9Y2P5 AB208931 BAD92168 AF064255 AAD29444 AK026640 AK123036 BAG53858 AK298446 BAG60663 BC146387 AAI46388 BC148807 AAI48808 BX103174 XM_011526363 XP_011524665 XM_011526364 XP_011524666 NM_012254 NP_036386
Function Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. {ECO:0000269|PubMed:10749848, ECO:0000269|PubMed:11980911}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10479480}; Multi-pass membrane protein {ECO:0000269|PubMed:10479480}.
Tissue Specificity Predominantly expressed in liver. {ECO:0000269|PubMed:10479480}.
Top Pathways Primary bile acid biosynthesis, PPAR signaling pathway, Bile secretion

Human SLC27A5 full length protein - ab161232 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161232 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SLC27A5 protein fragment - ab161233 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161233 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SLC27A5 / BACS Antibody Blocking Peptide - LS-E15312 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FATP5/SLC27A5 Protein - H00010998-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human FATP5/SLC27A5 Protein - H00010998-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SLC27A5-Antibody-Center-Blocking-Peptide - BP9015c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SLC27A5 Blocking Peptide - 33R-4549 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SLC27A5 / FATP5 - H00010998-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

SLC27A5 / FATP5 - H00010998-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

SLC27A5 / FATP5 - H00010998-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SLC27A5 / FATP5 - H00010998-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SLC27A5 fusion protein - ag18276 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

SLC27A5 fusion protein - Ag18446 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Fatty Acid Transport Protein 5 (FATP5) - RPB660Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Fatty Acid Transport Protein 5 (FATP5) - RPB660Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Fatty Acid Transport Protein 5 (FATP5) - RPB660Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Fatty Acid Transport Protein 5 (FATP5) - RPB660Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

FATP5 Blocking Peptide - CBP3388 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human

Recombinant Fatty Acid Transport Protein 5 (FATP5) - RPB660Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

FATP5/SLC27A5 Recombinant Protein Antigen - NBP1-89267PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

FATP5 Blocking Peptide - abx162250 from Abbexa

Category Peptide
Species Human

SLC27A5 Peptide, Human - M34GP14469H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

FATP5 Peptide - orb224274 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human

FATP5/SLC27A5 Recombinant Protein Antigen - NBP2-52880PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Source E. coli
Species Human

FATP5/SLC27A5 Recombinant Protein Antigen - NBP2-52881PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Source E. coli
Species Human
Search more