Gene Symbol |
CDH17
|
Entrez Gene |
1015
|
Alt Symbol |
CDH16, HPT-1, HPT1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cadherin 17, LI cadherin (liver-intestine)
|
Other Description |
HPT-1 cadherin|LI cadherin|LI-cadherin|cadherin-16|cadherin-17|human intestinal peptide-associated transporter HPT-1|human peptide transporter 1|intestinal peptide-associated transporter HPT-1|liver-intestine cadherin
|
Swissprots |
Q2M2E0 Q15336 Q12864
|
Accessions |
CAJ46925 EAW91708 Q12864 AI566493 AK130441 AK300638 BAG62327 AK301001 BAG62620 AK312873 BAG35725 AU098586 BC112013 AAI12014 BC113464 AAI13465 BF591263 BX483700 DB009107 HQ258682 ADR83433 U07969 AAA19021 X83228 CAA58231 XM_011516790 XP_011515092 NM_001144663 NP_001138135 NM_004063 NP_004054
|
Function |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. {ECO:0000269|PubMed:8153632}.
|
Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. {ECO:0000269|PubMed:8153632}.
|