CDH17
| Gene Symbol | CDH17 |
|---|---|
| Entrez Gene | 1015 |
| Alt Symbol | CDH16, HPT-1, HPT1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cadherin 17, LI cadherin (liver-intestine) |
| Other Description | HPT-1 cadherin|LI cadherin|LI-cadherin|cadherin-16|cadherin-17|human intestinal peptide-associated transporter HPT-1|human peptide transporter 1|intestinal peptide-associated transporter HPT-1|liver-intestine cadherin |
| Swissprots | Q2M2E0 Q15336 Q12864 |
| Accessions | CAJ46925 EAW91708 Q12864 AI566493 AK130441 AK300638 BAG62327 AK301001 BAG62620 AK312873 BAG35725 AU098586 BC112013 AAI12014 BC113464 AAI13465 BF591263 BX483700 DB009107 HQ258682 ADR83433 U07969 AAA19021 X83228 CAA58231 XM_011516790 XP_011515092 NM_001144663 NP_001138135 NM_004063 NP_004054 |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. {ECO:0000269|PubMed:8153632}. |
| Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. {ECO:0000269|PubMed:8153632}. |
LI-cadherin CRISPR/Cas9 KO Plasmid (h) - sc-401229 from Santa Cruz Biotechnology
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LI-cadherin HDR Plasmid (h) - sc-401229-HDR from Santa Cruz Biotechnology
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LI-cadherin Double Nickase Plasmid (h) - sc-401229-NIC from Santa Cruz Biotechnology
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LI-cadherin Double Nickase Plasmid (h2) - sc-401229-NIC-2 from Santa Cruz Biotechnology
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LI-cadherin CRISPR Activation Plasmid (h) - sc-401229-ACT from Santa Cruz Biotechnology
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LI-cadherin CRISPR Activation Plasmid (h2) - sc-401229-ACT-2 from Santa Cruz Biotechnology
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LI-cadherin Lentiviral Activation Particles (h) - sc-401229-LAC from Santa Cruz Biotechnology
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LI-cadherin Lentiviral Activation Particles (h2) - sc-401229-LAC-2 from Santa Cruz Biotechnology
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LI-cadherin siRNA (h) - sc-43013 from Santa Cruz Biotechnology
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LI-cadherin shRNA Plasmid (h) - sc-43013-SH from Santa Cruz Biotechnology
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LI-cadherin shRNA (h) Lentiviral Particles - sc-43013-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU043961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5813 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5813 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07760 from Sigma-Aldrich
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CDH17 siRNA (Human) - CRH0728 from Cohesion Biosciences
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Cadherin-17 RNAi - H00001015-R01 from Novus Biologicals
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CDH17 - MBS8223213 from MyBioSource
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LI-cadherin CRISPR/Cas9 KO Plasmid (h2) - sc-401229-KO-2 from Santa Cruz Biotechnology
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LI-cadherin HDR Plasmid (h2) - sc-401229-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CDH17 (NM_004063.3) - SHH260197 from Creative biogene
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CDH17 shRNA Plasmid (Human) - CHH0728 from Cohesion Biosciences
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CDH17 miRNA 3'UTR clone - MiUTR3H-05558 from Creative biogene
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CDH17 miRNA 3'UTR clone - MiUTR3H-05559 from Creative biogene
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