Gene Symbol | CDH17 |
---|---|
Entrez Gene | 1015 |
Alt Symbol | CDH16, HPT-1, HPT1 |
Species | Human |
Gene Type | protein-coding |
Description | cadherin 17, LI cadherin (liver-intestine) |
Other Description | HPT-1 cadherin|LI cadherin|LI-cadherin|cadherin-16|cadherin-17|human intestinal peptide-associated transporter HPT-1|human peptide transporter 1|intestinal peptide-associated transporter HPT-1|liver-intestine cadherin |
Swissprots | Q2M2E0 Q15336 Q12864 |
Accessions | CAJ46925 EAW91708 Q12864 AI566493 AK130441 AK300638 BAG62327 AK301001 BAG62620 AK312873 BAG35725 AU098586 BC112013 AAI12014 BC113464 AAI13465 BF591263 BX483700 DB009107 HQ258682 ADR83433 U07969 AAA19021 X83228 CAA58231 XM_011516790 XP_011515092 NM_001144663 NP_001138135 NM_004063 NP_004054 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. {ECO:0000269|PubMed:8153632}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. {ECO:0000269|PubMed:8153632}. |