Gene Symbol | DDX17 |
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Entrez Gene | 10521 |
Alt Symbol | P72, RH70 |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
Other Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17|DEAD box protein p72|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)|RNA-dependent helicase p72|probable ATP-dependent RNA helicase DDX17 |
Swissprots | Q69YT1 Q6ICD6 Q92841 B1AHM0 |
Accessions | EAW60241 EAW60242 EAW60243 EAW60244 EAW60245 EAW60246 EAW60247 EAW60248 Q92841 AA765457 AB209595 BAD92832 AF131750 AAD20033 AK024985 AK074224 AK303049 BAG64169 AL080113 AL713763 CAH10627 AU130891 BC000595 AAH00595 BC029553 BC045747 BI545691 BP353248 CB215934 CR456432 CAG30318 CU012992 CAK54423 CU013280 CAK54722 U59321 AAC50787 NM_001098504 NP_001091974 NM_006386 NP_006377 NM_001098505 NM_030881 |
Function | RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. {ECO:0000269|PubMed:11250900, ECO:0000269|PubMed:15298701, ECO:0000269|PubMed:17011493, ECO:0000269|PubMed:17226766, ECO:0000269|PubMed:18334637, ECO:0000269|PubMed:19718048}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22002106}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106}. |
Tissue Specificity | Ubiquitous. |
DDX17 (B-6) - sc-376297 from Santa Cruz Biotechnology
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DDX17 (C-9) - sc-271112 from Santa Cruz Biotechnology
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DDX17 (F-4) - sc-376396 from Santa Cruz Biotechnology
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DDX17 (H-7) - sc-398168 from Santa Cruz Biotechnology
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DDX17 (H-157) - sc-98641 from Santa Cruz Biotechnology
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DDX17 (S-17) - sc-86409 from Santa Cruz Biotechnology
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DDX17 (N-13) - sc-86408 from Santa Cruz Biotechnology
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Anti-DDX17 antibody - ab24601 from Abcam
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Anti-DDX17 antibody - ab70184 from Abcam
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Anti-DDX17 antibody [2248C2a] - ab71958 from Abcam
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Anti-DDX17 antibody [EPR13807(B)] - C-terminal - ab180190 from Abcam
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Anti-DDX17 Antibody (clone 2248C2a) - LS-C64586 from LifeSpan Bioscience
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Anti-DDX17 Antibody (C-Terminus) - LS-C64588 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, AP) - LS-C213525 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, APC) - LS-C213526 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, FITC) - LS-C213527 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, Biotin) - LS-C213528 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, Azide-free, HRP) - LS-C213529 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85, PE) - LS-C213530 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa570-619) - LS-C31694 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa55-85) - LS-C320777 from LifeSpan Bioscience
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Anti-DDX17 Antibody (clone 2248C2a) - LS-C184675 from LifeSpan Bioscience
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Anti-DDX17 Antibody (aa107-156) - LS-C110150 from LifeSpan Bioscience
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Anti-DDX17 Antibody (C-Terminus) - LS-C286401 from LifeSpan Bioscience
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Anti-DDX17 Antibody - LS-C334417 from LifeSpan Bioscience
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