| Gene Symbol |
DDX17
|
| Entrez Gene |
10521
|
| Alt Symbol |
P72, RH70
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DEAD (Asp-Glu-Ala-Asp) box helicase 17
|
| Other Description |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17|DEAD box protein p72|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)|RNA-dependent helicase p72|probable ATP-dependent RNA helicase DDX17
|
| Swissprots |
Q69YT1 Q6ICD6 Q92841 B1AHM0
|
| Accessions |
EAW60241 EAW60242 EAW60243 EAW60244 EAW60245 EAW60246 EAW60247 EAW60248 Q92841 AA765457 AB209595 BAD92832 AF131750 AAD20033 AK024985 AK074224 AK303049 BAG64169 AL080113 AL713763 CAH10627 AU130891 BC000595 AAH00595 BC029553 BC045747 BI545691 BP353248 CB215934 CR456432 CAG30318 CU012992 CAK54423 CU013280 CAK54722 U59321 AAC50787 NM_001098504 NP_001091974 NM_006386 NP_006377 NM_001098505 NM_030881
|
| Function |
RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. {ECO:0000269|PubMed:11250900, ECO:0000269|PubMed:15298701, ECO:0000269|PubMed:17011493, ECO:0000269|PubMed:17226766, ECO:0000269|PubMed:18334637, ECO:0000269|PubMed:19718048}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:22002106}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106}.
|
| Tissue Specificity |
Ubiquitous.
|
![Western Blot: DDX17 Overexpression Lysate (Adult Normal) [NBL1-09782] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DDX17.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11943_DDX17%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09782-img0002.jpg)