CFB

Gene Symbol CFB
Entrez Gene 629
Alt Symbol AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
Species Human
Gene Type protein-coding
Description complement factor B
Other Description B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|glycine-rich beta glycoprotein|glycine-rich beta-glycoprotein|properdin factor B
Swissprots Q5JP67 Q53F89 Q5ST50 O15006 P00751 Q9BX92 Q96HX6 Q9BTF5 B0QZQ6 Q29944
Accessions AAA59625 AAB67977 AAN71991 AAQ13379 AAQ13380 AAQ13401 EAX03550 P00751 AF349679 AAK30167 AK130533 AK223400 BAD97120 AK304042 BAG64953 AL701961 BC004143 AAH04143 BC007990 AAH07990 BI258352 CD689714 DC368322 DQ892313 ABM83239 DQ895516 ABM86442 J00126 AAA36226 J00185 AAA36219 J00186 AAA36220 K01566 AAA36225 L15702 AAA16820 S67310 AAD13989 X00284 CAA25077 X72875 CAA51389 NM_001710 NP_001701
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection

Factor B (D22/3) - sc-47681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (D22/3): sc-47681. Western blot analysis of purified human Factor B.

Factor B (H-95) - sc-67141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Factor B (H-95): sc-67141. Western blot analysis of Factor B expression in Human Factor B fusion protein whole cell lysate.

Factor B (M13/12) - sc-47682 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (M13/12): sc-47682. Western blot analysis of purified human Factor B.

Factor B (N-14) - sc-34888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Factor B (N-14): sc-34888. Western blot analysis of Factor B in human plasma.

Factor B (P21/15) - sc-47679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (P21/15): sc-47679. Western blot analysis of purified human Factor B.

Factor B (F-7) - sc-271636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (F-7): sc-271636. Western blot analysis of Factor B expression in non-transfected: sc-110760 (A) and human Factor B transfected: sc-159858 (B) 293 whole cell lysates.

Factor B (M20/6) - sc-47680 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (M20/6): sc-47680. Western blot analysis of purified human Factor B.

Factor B (28A3) - sc-69772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (28A3): sc-69772. Western blot analysis of Factor B purified from human plasma (A) and in human plasma (B).

Factor B (9B6) - sc-57506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Factor B (9B6): sc-57506. Western blot analysis of Factor B expression in non-transfected: sc-117752 (A) and human Factor B transfected: sc-170756 (B) 293T whole cell lysates .

Anti-Complement factor B antibody [EPR9287(B)] - ab140647 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9287(B)
All lanes : Anti-Complement factor B antibody [EPR9287(B)] (ab140647) at 1/1000 dilutionLane 1 : Human serumLane 2 : Human plasmaLysates/proteins at 10 µg per lane.SecondaryHRP conjugated goat anti-rabbit at 1/2000 dilution

Anti-Complement factor B antibody [EPR9288(B)] - ab133765 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9288(B)
All lanes : Anti-Complement factor B antibody [EPR9288(B)] (ab133765) at 1/1000 dilutionLane 1 : Human serum lysateLane 2 : Human plasma lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-Complement factor B antibody [M13/12] - ab106139 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone M13/12

Anti-Factor B antibody - ab182924 from Abcam

Host Goat
Clonality Polyclonal

Anti-Factor B antibody - ab176024 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human hepatocarcinoma tissue labeling Factor B with ab176024 at 1/50, followed by peroxidase conjugation of the secondary antibody and DAB staining

Anti-Factor B antibody - ab72658 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Factor B antibody (ab72658) at 1/200 dilutionLane 1 : Extracts from K562 cells, treated with etoposide (25uM, 1hour)Lane 2 : Extracts from K562 cells, treated with etoposide (25uM, 1hour) with Cl-peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Factor B antibody - ab192577 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Factor B antibody - ab150494 from Abcam

Prices $407.00
Sizes 1 ml
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labelling Factor B with ab150494 at 1/200 dilution.

Anti-Factor B antibody [6G11] - ab17927 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6G11

Anti-Factor B antibody [9B6] - ab26040 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9B6

Anti-Factor B antibody [9B8] - ab17932 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9B8

Anti-Factor B antibody [KT21] - ab110651 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone KT21
Sandwich ELISA using ab110651 coated plate and HRP conjugated ab106687 for detection.

Anti-Factor B antibody [KT21] - ab53366 from Abcam

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone KT21

Anti-Factor B antibody [KT24] (HRP) - ab106687 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone KT24
Sandwich ELISA showing ab106687 at 1/1000 dilution as detection antibody.

Anti-CFB / Complement Factor B Antibody - LS-C22334 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CFB / Complement Factor B Antibody - LS-C22336 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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