CFB

Gene Symbol	CFB
Entrez Gene	629
Alt Symbol	AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
Species	Human
Gene Type	protein-coding
Description	complement factor B
Other Description	B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|glycine-rich beta glycoprotein|glycine-rich beta-glycoprotein|properdin factor B
Swissprots	Q5JP67 Q53F89 Q5ST50 O15006 P00751 Q9BX92 Q96HX6 Q9BTF5 B0QZQ6 Q29944
Accessions	AAA59625 AAB67977 AAN71991 AAQ13379 AAQ13380 AAQ13401 EAX03550 P00751 AF349679 AAK30167 AK130533 AK223400 BAD97120 AK304042 BAG64953 AL701961 BC004143 AAH04143 BC007990 AAH07990 BI258352 CD689714 DC368322 DQ892313 ABM83239 DQ895516 ABM86442 J00126 AAA36226 J00185 AAA36219 J00186 AAA36220 K01566 AAA36225 L15702 AAA16820 S67310 AAD13989 X00284 CAA25077 X72875 CAA51389 NM_001710 NP_001701
Function	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CFB overexpression lysate - LY400641 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CFB 293 Cell Lysate - 400631 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Complement Factor B Overexpression Lysate (Native) - NBL1-09119 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Factor B (h): 293 Lysate - sc-159858 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Factor B (h2): 293T Lysate - sc-170756 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CFB Over-expression Lysate Product - GWB-AA54A8 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human Complement Factor B Deficient Plasma (EDTA) - D700104 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (EDTA) - D700105 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (EDTA) - D700106 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Heparin) - D700107 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Heparin) - D700108 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Heparin) - D700109 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Sodium Citrate) - D700101 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Sodium Citrate) - D700102 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement Factor B Deficient Plasma (Sodium Citrate) - D700103 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement Factor B Deficient Serum - D700110 from AssayPro Category Blood Product Prices $20.00 Sizes 1 ml Species Human Tissue Serum

Human Complement Factor B Deficient Serum - D700111 from AssayPro Category Blood Product Prices $180.00 Sizes 10 ml Species Human Tissue Serum

Human Complement Factor B Deficient Serum - D700112 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Serum

Panoply™ Human CFB Knockdown Stable Cell Line - CSC-DC003028 from Creative biogene Category Cell Line Species Human

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