CFB

Gene Symbol	CFB
Entrez Gene	629
Alt Symbol	AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
Species	Human
Gene Type	protein-coding
Description	complement factor B
Other Description	B-factor, properdin|C3 proaccelerator|C3 proactivator|C3/C5 convertase|glycine-rich beta glycoprotein|glycine-rich beta-glycoprotein|properdin factor B
Swissprots	Q5JP67 Q53F89 Q5ST50 O15006 P00751 Q9BX92 Q96HX6 Q9BTF5 B0QZQ6 Q29944
Accessions	AAA59625 AAB67977 AAN71991 AAQ13379 AAQ13380 AAQ13401 EAX03550 P00751 AF349679 AAK30167 AK130533 AK223400 BAD97120 AK304042 BAG64953 AL701961 BC004143 AAH04143 BC007990 AAH07990 BI258352 CD689714 DC368322 DQ892313 ABM83239 DQ895516 ABM86442 J00126 AAA36226 J00185 AAA36219 J00186 AAA36220 K01566 AAA36225 L15702 AAA16820 S67310 AAD13989 X00284 CAA25077 X72875 CAA51389 NM_001710 NP_001701
Function	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Factor B Human ELISA Kit - ab137973 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity 4.3 ng/ml Range 4.375 ng/ml - 280 ng/ml

Mouse CFB / Complement Factor B ELISA Kit (Sandwich ELISA) - LS-F5963 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.78 ng/ml Range 1.25-80 ng/ml

Rat CFB / Complement Factor B ELISA Kit (Sandwich ELISA) - LS-F5964 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 6.25 ng/ml Range 1.25-80 ng/ml

Human CFB / Complement Factor B ELISA Kit (Sandwich ELISA) - LS-F5282 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 1.25 ng/ml Range 1.25-80 ng/ml

Human CFB / Complement Factor B ELISA Kit (Sandwich ELISA) - LS-F11118 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.625 ng/ml Range 1.25-80 ng/ml

Human Complement Factor B ELISA Kit - abx151138 from Abbexa Category ELISA Kit Sensitivity 1.35 ng/ml Range 3.125 ng/ml - 200 ng/ml

Factor B, BF, Human, ELISA Kit - E-EL-H0848 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Complement Factor B, CFB, Human, ELISA Kit - E-EL-H0814 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Complement Factor B (CFB), Human, ELISA Kit - SEC011Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 1.37ng/mL Range 3.12-200ng/mL

Complement factor B, CFB, Human, ELISA Kit - E2011h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 62.5-4000 ng/mL

Complement Factor B, Human, ELISA Kit - E01C0365 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 2.5-50ng/mL,

Factor B, BF, Human, ELISA Kit - CSB-E09447h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Fibrinogen (FB), Human, ELISA Kit - CSB-E13656h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ?g/ml Range 0.312 ?g/ml-20 ?g/ml

Properdin (CFP), Human, ELISA Kit - CSB-EL005291HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.12 ng/ml Range 12.5 ng/ml-800 ng/ml

factor B, BF, Mouse, ELISA Kit - E-EL-M0483 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Complement Factor B, CFB, Mouse, ELISA Kit - E-EL-M0334 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Complement Factor B, CFB, Rat, ELISA Kit - E-EL-R0253 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Factor B, BF, Rabbit, ELISA Kit - E-EL-RB2205 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Complement Factor B, CFB, Rabbit, ELISA Kit - E-EL-RB1297 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Factor B, BF, Chicken, ELISA Kit - E-EL-Ch0616 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Complement Factor B, CFB, Chicken, ELISA Kit - E-EL-Ch0730 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Factor B, BF, Porcine, ELISA Kit - E-EL-P1316 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Complement Factor B, CFB, Porcine, ELISA Kit - E-EL-P1486 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Factor B, BF, Sheep, ELISA Kit - E-EL-S0241 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Complement Factor B, CFB, Guinea Pig, ELISA Kit - E-EL-GP0131 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

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