Bnip3

Gene Symbol Bnip3
Entrez Gene 12176
Alt Symbol Nip3
Species Mouse
Gene Type protein-coding
Description BCL2/adenovirus E1B interacting protein 3
Other Description BCL2/adenovirus E1B 19 kDa protein-interacting protein 3|BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3|BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3|BCL2/adenovirus E1B interacting protein 1, NIP3
Swissprots O55003 Q544Y4
Accessions EDL17839 EDL17840 O55003 AF041054 AAD02922 AK014223 BAB29214 AK075943 BAC36072 AK152610 BAE31356 AK170865 AV091103 BC033278 BC046603 AAH46603 NM_009760 NP_033890
Function Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2 (By similarity). Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity). The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity). Plays an importa
Subcellular Location Mitochondrion. Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane (By similarity). {ECO:0000250}.
Top Pathways Legionellosis

NIP3-BH3-Domain-Peptide - SP1019a from Abgent, a WuXi AppTec company

Category Peptide
Prices $150.00
Sizes 1 mg

Recombinant Mouse BNIP3 Protein - BNIP3-2448M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (Bnip3), Recombinant Protein - MBS1046915 from MyBioSource

Category Protein
Prices $935.00, $935.00, $1,155.00, $1,155.00, $1,335.00, $1,335.00, $1,795.00, $1,795.00, $1,795.00, $2,595.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (Bnip3), Recombinant Protein - MBS7010439 from MyBioSource

Category Protein
Prices $1,005.00, $1,990.00, $3,200.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Mouse

Recombinant Mouse BNIP3 Protein (1-156 aa), His-tagged - BNIP3-2403M from Creative Biomart

Category Protein
Source E. coli
Species Mouse
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