AMOT

Gene Symbol AMOT
Entrez Gene 154796
Alt Symbol -
Species Human
Gene Type protein-coding
Description angiomotin
Other Description angiomotin p130 isoform|angiomotin p80 isoform
Swissprots Q4VCS5 Q9HD27 Q9UPT1 Q504X5
Accessions EAX02626 EAX02627 Q4VCS5 AB028994 BAA83023 AF286598 AAG01851 AK024344 AK301573 BAG63066 AY987378 AAY24451 BC039408 BC050581 BC094712 AAH94712 BC130294 AAI30295 XM_005262087 XP_005262144 XM_005262088 XP_005262145 XM_005262090 XP_005262147 XM_011530875 XP_011529177 NM_001113490 NP_001106962 NM_133265 NP_573572
Function Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. {ECO:0000269|PubMed:11257124, ECO:0000269|PubMed:16678097}.
Subcellular Location Cell junction, tight junction {ECO:0000269|PubMed:16043488}. Note=Localized on the cell surface. May act as a transmembrane protein.
Tissue Specificity Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta. {ECO:0000269|PubMed:11257124}.
Top Pathways Hippo signaling pathway

Angiomotin (B-4) - sc-166924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Angiomotin (B-4): sc-166924. Western blot analysis of Angiomotin expression in 293T whole cell lysate.

Angiomotin (C-18) - sc-82491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Angiomotin (C-18): sc-82491. Western blot analysis of Angiomotin expression in 293T whole cell lysate.

Angiomotin (H-66) - sc-98803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Angiomotin (H-66): sc-98803. Western blot analysis of Angiomotin expression in 293T (A), MCF7 (B) and HeLa (C) whole cell lysates.

Angiomotin (L-16) - sc-82493 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Angiomotin (L-16): sc-82493. Western blot analysis of Angiomotin expression in 293T (A) and MCF7 (B) whole cell lysates.

Angiomotin (S-20) - sc-82494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Angiomotin antibody - ab85143 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Angiomotin antibody (ab85143) at 1 µg/ml + Placenta (Human) Tissue Lysate - adult normal tissue (ab29745) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Angiomotin antibody [1A8] - ab180365 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A8
All lanes : Anti-Angiomotin antibody [1A8] (ab180365) at 1/1000 dilutionLane 1 : Non-transfected HEK293T cell lysateLane 2 : Angiomotin transfected HEK293T cell lysateLysates/proteins at 5 µg per lane.

Anti-AMOT / Angiomotin Antibody (aa238-267, Biotin) - LS-C232606 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (aa238-267, FITC) - LS-C232608 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (aa238-267, AP) - LS-C232605 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (aa238-267, APC) - LS-C232607 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041, Biotin) - LS-C232611 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (aa238-267, PE) - LS-C232609 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041, FITC) - LS-C232612 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Tyr599, APC) - LS-C232615 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Tyr599, Biotin) - LS-C232616 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041, AP) - LS-C232610 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041, PE) - LS-C232613 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Tyr599, AP) - LS-C232614 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Tyr599, FITC) - LS-C232617 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041) - LS-C161057 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot of Phospho-AMOT-S1041 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Anti-AMOT / Angiomotin Antibody (phospho-Tyr599, PE) - LS-C232618 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (phospho-Ser1041, APC) - LS-C248990 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMOT / Angiomotin Antibody (aa108-157) - LS-C109951 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AMOT / Angiomotin antibody LS-C109951 Western blot of Fetal Heart lysate.

Anti-AMOT / Angiomotin Antibody (aa108-157) - LS-C101511 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AMOT / Angiomotin antibody LS-C101511 Western blot of 293T cell lysate.
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