AMOT

Gene Symbol AMOT
Entrez Gene 154796
Alt Symbol -
Species Human
Gene Type protein-coding
Description angiomotin
Other Description angiomotin p130 isoform|angiomotin p80 isoform
Swissprots Q4VCS5 Q9HD27 Q9UPT1 Q504X5
Accessions EAX02626 EAX02627 Q4VCS5 AB028994 BAA83023 AF286598 AAG01851 AK024344 AK301573 BAG63066 AY987378 AAY24451 BC039408 BC050581 BC094712 AAH94712 BC130294 AAI30295 XM_005262087 XP_005262144 XM_005262088 XP_005262145 XM_005262090 XP_005262147 XM_011530875 XP_011529177 NM_001113490 NP_001106962 NM_133265 NP_573572
Function Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions. {ECO:0000269|PubMed:11257124, ECO:0000269|PubMed:16678097}.
Subcellular Location Cell junction, tight junction {ECO:0000269|PubMed:16043488}. Note=Localized on the cell surface. May act as a transmembrane protein.
Tissue Specificity Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta. {ECO:0000269|PubMed:11257124}.
Top Pathways Hippo signaling pathway

Angiomotin CRISPR/Cas9 KO Plasmid (h) - sc-400940 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin HDR Plasmid (h) - sc-400940-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin Double Nickase Plasmid (h) - sc-400940-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin Double Nickase Plasmid (h2) - sc-400940-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin CRISPR Activation Plasmid (h) - sc-400940-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin CRISPR Activation Plasmid (h2) - sc-400940-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin Lentiviral Activation Particles (h) - sc-400940-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin Lentiviral Activation Particles (h2) - sc-400940-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiomotin siRNA (h) - sc-72489 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiomotin shRNA Plasmid (h) - sc-72489-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiomotin shRNA (h) Lentiviral Particles - sc-72489-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AMOT RNAi - H00154796-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU129771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3121 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3121 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AMOT siRNA (Human) - CRJ5802 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AMOT - MBS8217092 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AMOT (NM_133265.2) - SHH235858 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AMOT(NM_133265.2) - SHG056369 from Creative biogene

Category siRNA
Species Reactivities Human

Human AMOT siRNA - orb276303 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AMOT shRNA Plasmid (Human) - CHJ5802 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AMOT miRNA 3'UTR clone - MiUTR1H-00340 from Creative biogene

Species Reactivities Human
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