| Gene Symbol |
PFAS
|
| Entrez Gene |
5198
|
| Alt Symbol |
FGAMS, FGAR-AT, FGARAT, PURL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoribosylformylglycinamidine synthase
|
| Other Description |
FGAM synthase|FGAR amidotransferase|formylglycinamide ribonucleotide amidotransferase|formylglycinamide ribotide amidotransferase|formylglycinamide ribotide synthetase
|
| Swissprots |
O15067 A6H8V8
|
| Accessions |
EAW90067 EAW90068 EAW90069 O15067 AB002359 BAA20816 AK292402 BAF85091 AK292804 BAF85493 AK295895 BAG58688 AL044326 AY545554 BC006522 AAH06522 BC009318 BC031807 BC063538 AAH63538 BC146768 AAI46769 BC167158 AAI67158 DQ576789 XM_006721546 XP_006721609 XM_011523937 XP_011522239 XM_011523938 XP_011522240 XR_934047 NM_012393 NP_036525
|
| Function |
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Top Pathways |
Purine metabolism
|