PFAS

Gene Symbol PFAS
Entrez Gene 5198
Alt Symbol FGAMS, FGAR-AT, FGARAT, PURL
Species Human
Gene Type protein-coding
Description phosphoribosylformylglycinamidine synthase
Other Description FGAM synthase|FGAR amidotransferase|formylglycinamide ribonucleotide amidotransferase|formylglycinamide ribotide amidotransferase|formylglycinamide ribotide synthetase
Swissprots O15067 A6H8V8
Accessions EAW90067 EAW90068 EAW90069 O15067 AB002359 BAA20816 AK292402 BAF85091 AK292804 BAF85493 AK295895 BAG58688 AL044326 AY545554 BC006522 AAH06522 BC009318 BC031807 BC063538 AAH63538 BC146768 AAI46769 BC167158 AAI67158 DQ576789 XM_006721546 XP_006721609 XM_011523937 XP_011522239 XM_011523938 XP_011522240 XR_934047 NM_012393 NP_036525
Function Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Purine metabolism

FGAM Synthase (N-15) - sc-139139 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PFAS antibody - ab82755 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PFAS antibody (ab82755) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PFAS antibody - ab186013 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PFAS antibody (ab186013) at 0.04 µg/mlLane 1 : HeLa whole cell lysateLane 2 : 293T whole cell lysateLane 3 : Jurkat whole cell lysateLane 4 : TCMK-1 whole cell lysateLane 5 : NIH3T3 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-PFAS antibody - ab186042 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PFAS antibody - N-terminal - ab174331 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFAS antibody - N-terminal (ab174331) at 100 µg + HepG2 cell line lysate at 35 µg

Anti-PFAS Antibody (aa252-301) IHC-plus™ - LS-B11134 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PFAS antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11134 concentration 15 ug/ml.

Anti-PFAS Antibody (aa184-213, AP) - LS-C267596 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa184-213, APC) - LS-C267597 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa184-213, Biotin) - LS-C267598 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa184-213, Azide-free, HRP) - LS-C267599 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa184-213, FITC) - LS-C267600 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa184-213, PE) - LS-C267601 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa191-221) - LS-C324429 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFAS Antibody (aa925-975) - LS-C290862 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PFAS by Western Blot. Samples: Whole cell lysate (50 ug) from Jurkat, HeLa, and 293T cells. Antibodies: Affinity purified rabbit anti-PFAS antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-PFAS Antibody (aa875-925) - LS-C290861 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PFAS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-PFAS antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-PFAS Antibody (aa184-213) - LS-C162323 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PUR4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PFAS Antibody (aa1-50) - LS-C290860 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PFAS by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-PFAS antibody used for IP at 6 ug/mg lysate. For blotting immunoprecipitated PFAS, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

PURL Antibody - NBP1-84691 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PURL Antibody [NBP1-84691] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

PURL Antibody - NBP1-70692 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PURL Antibody [NBP1-70692] - 293T Whole Cell lysates, Antibody Dilution: 0.05 ug/ml.

PURL Antibody - NBP1-84692 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PURL Antibody [NBP1-84692] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

ANTI-PUR4 (N-TERMINAL) antibody produced in rabbit - SAB1306491 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PUR4 (N-term): <B>Cat. No. SAB1306491</B>: Western blot analysis of PUR4 Antibody (N-term) in HepG2 cell line lysates (35 μg/lane).

Anti-PFAS antibody produced in rabbit - SAB2101776 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PFAS: <B>Cat. No.SAB2101776</B>: PFAS in 293T cell lysate with PFAS antibody at 1.0 μg/mL.

Anti-PFAS antibody produced in rabbit - HPA022140 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PFAS: <B>Cat. No. HPA022140</B>: Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.

PFAS antibody - N-terminal region (ARP46181_P050) - ARP46181_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PFAS Antibody - N-terminal region (OAAB02169) - OAAB02169 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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