Gene Symbol | NACA2 |
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Entrez Gene | 342538 |
Alt Symbol | ANAC, NACAL |
Species | Human |
Gene Type | protein-coding |
Description | nascent polypeptide-associated complex alpha subunit 2 |
Other Description | IgE autoantigen alpha-nascent polypeptide-associated complex|alpha-NAC protein|hom s 2.01 protein|nascent polypeptide-associated complex subunit alpha-2|nascent polypeptide-associated complex, alpha polypeptide, 2 |
Swissprots | Q2VIR9 Q9H009 |
Accessions | ABB92399 CAC06614 Q9H009 BC062710 AAH62710 HQ447566 ADQ32052 NM_199290 NP_954984 |
Function | Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed specifically in testis and skeletal muscle. {ECO:0000269|PubMed:16201836}. |
Human NACA2 full length protein - ab166298 from Abcam
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Human NACA2 full length protein - ab88940 from Abcam
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Human NACA2 protein fragment - ab166299 from Abcam
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Recombinant Human NACA2 Protein - H00342538-P01 from Novus Biologicals
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Recombinant Human NACA2 Protein - H00342538-Q01 from Novus Biologicals
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Human NACA2 Protein - abx060051 from Abbexa
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NACA2 - H00342538-P01-10 from Acris Antibodies
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NACA2 - H00342538-P01-25 from Acris Antibodies
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NACA2 - H00342538-Q01-10 from Acris Antibodies
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NACA2 - H00342538-Q01-25 from Acris Antibodies
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Recombinant Human NACA2 - NACA2-28774TH from Creative Biomart
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Recombinant Human Nascent polypeptide-associated complex subunit alpha-2(NACA2) - CSB-YP887940HU CSB-EP887940HU CSB-BP887940HU CSB-MP887940HU from Cusabio
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NACA2-Blocking-Peptide-N-Term - BP21718a from Abgent, a WuXi AppTec company
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NACA2 Peptide, Human - M34GP10093H from Creative Peptides
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Nascent polypeptide-associated complex subunit alpha-2 (NACA2), Recombinant Protein - MBS1319994 from MyBioSource
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Recombinant Human ANAC protein, GST-tagged - ANAC-539H from Creative Biomart
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