Gene Symbol | LIF |
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Entrez Gene | 3976 |
Alt Symbol | CDF, DIA, HILDA, MLPLI |
Species | Human |
Gene Type | protein-coding |
Description | leukemia inhibitory factor |
Other Description | D factor|cholinergic differentiation factor|differentiation inhibitory activity|differentiation-inducing factor|differentiation-stimulating factor|hepatocyte-stimulating factor III|human interleukin in DA cells|melanoma-derived LPL inhibitor |
Swissprots | B5MC23 B2RCW7 Q52LZ2 P15018 |
Accessions | AAA51699 AAA53188 AAA59517 AAC05174 EAW59863 P15018 AI796373 AK315310 BAG37714 BC069540 AAH69540 BC093733 AAH93733 BC093735 AAH93735 BC143305 CK819709 CN409458 X13967 CAA32147 XM_006724240 XP_006724303 XM_011530172 XP_011528474 NM_001257135 NP_001244064 NM_002309 NP_002300 |
Function | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, TNF signaling pathway, Signaling pathways regulating pluripotency of stem cells |
SignalKine™ Human LIF Chemiluminescent Sandwich ELISA Kit - 12031 from Cell Signaling Technology
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SignalKine™ Human LIF Sandwich ELISA Kit - 11928 from Cell Signaling Technology
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LIF Human ELISA Kit - ab100582 from Abcam
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Human LIF ELISA Kit (Sandwich ELISA) - LS-F5122 from LifeSpan Bioscience
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Pig LIF ELISA Kit (Sandwich ELISA) - LS-F6146 from LifeSpan Bioscience
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Human LIF ELISA Kit (Sandwich ELISA) - LS-F139 from LifeSpan Bioscience
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Human LIF ELISA Kit - RAB0339 from Sigma-Aldrich
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Human LIF Quantikine ELISA Kit - DLF00 from R&D Systems
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Mouse LIF Quantikine ELISA Kit - MLF00 from R&D Systems
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Human LIF DuoSet ELISA - DY7734-05 from R&D Systems
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Quantikine Immunoassay Control Set 582 for Human LIF - QC113 from R&D Systems
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Human LIF ELISA kit - 55R-IB49639 from Fitzgerald
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Human LIF ELISA kit - 55R-2054 from Fitzgerald
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Human Leukemia Inhibitory Factor ELISA Kit - abx053579 from Abbexa
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Human LIF ELISA Kit - abx152198 from Abbexa
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Human LIF ELISA Kit - abx056256 from Abbexa
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Leukemia Inhibitory Factor (LIF), Human, ELISA Kit - SEA085Hu from ARP American Research Products
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Leukemia Inhibitory Factor, Human, ELISA Kit - E01L0007 from ARP American Research Products
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Leukemia inhibitory factor, LIF, Human, ELISA Kit - CSB-E04651h from ARP American Research Products
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Leukemia inhibitory factor, LIF, Human, ELISA Kit - E0085h from ARP American Research Products
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Leukemia Inhibitory Factor, LIF, Human, ELISA Kit - E-EL-H0094 from ARP American Research Products
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LIF, Human, ELISA - IB49639 from ARP American Research Products
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Leukemia Inhibitory Factor, LIF, Mouse, ELISA Kit - E-EL-M0040 from ARP American Research Products
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Leukemia Inhibitory Factor, LIF, Rat, ELISA Kit - E-EL-R0585 from ARP American Research Products
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Leukemia Inhibitory Factor, LIF, Rabbit, ELISA Kit - E-EL-RB0269 from ARP American Research Products
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