Gene Symbol | LIF |
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Entrez Gene | 3976 |
Alt Symbol | CDF, DIA, HILDA, MLPLI |
Species | Human |
Gene Type | protein-coding |
Description | leukemia inhibitory factor |
Other Description | D factor|cholinergic differentiation factor|differentiation inhibitory activity|differentiation-inducing factor|differentiation-stimulating factor|hepatocyte-stimulating factor III|human interleukin in DA cells|melanoma-derived LPL inhibitor |
Swissprots | B5MC23 B2RCW7 Q52LZ2 P15018 |
Accessions | AAA51699 AAA53188 AAA59517 AAC05174 EAW59863 P15018 AI796373 AK315310 BAG37714 BC069540 AAH69540 BC093733 AAH93733 BC093735 AAH93735 BC143305 CK819709 CN409458 X13967 CAA32147 XM_006724240 XP_006724303 XM_011530172 XP_011528474 NM_001257135 NP_001244064 NM_002309 NP_002300 |
Function | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, TNF signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Active human LIF full length protein - ab57665 from Abcam
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Active human LIF full length protein - ab193881 from Abcam
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Active human LIF full length protein - ab188052 from Abcam
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Active human LIF full length protein - ab188058 from Abcam
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Active human LIF full length protein - ab99450 from Abcam
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Active mouse LIF full length protein - ab180030 from Abcam
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Active mouse LIF full length protein - ab181971 from Abcam
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Active mouse LIF full length protein - ab193074 from Abcam
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Mouse LIF full length protein - ab123757 from Abcam
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DIAPH2 Antibody Blocking Peptide - LS-E22539 from LifeSpan Bioscience
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DIAPH2 Antibody Blocking Peptide - LS-E10113 from LifeSpan Bioscience
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LIF Antibody Blocking Peptide - LS-E8581 from LifeSpan Bioscience
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LIF Antibody Blocking Peptide - LS-E28011 from LifeSpan Bioscience
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LIF Antibody Blocking Peptide - LS-E31097 from LifeSpan Bioscience
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Recombinant Human LIF Protein - NBP2-34935 from Novus Biologicals
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LIF Recombinant Protein - H00003976-P01 from Novus Biologicals
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LIF Recombinant Protein - P3646 from Novus Biologicals
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LIF Blocking Peptide - NBP1-76554PEP from Novus Biologicals
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LIF Protein - NBP1-99551 from Novus Biologicals
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LIF Protein - NBP1-99688 from Novus Biologicals
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Recombinant Human LIF Protein - NBP1-49444 from Novus Biologicals
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LIF-Antibody-Center-Blocking-Peptide - BP6981c from Abgent, a WuXi AppTec company
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LIF recombinant protein - GTX65165 from GeneTex
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LIF recombinant protein - GTX65164 from GeneTex
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Recombinant Human LIF - 7734-LF-025 from R&D Systems
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