Mesp2

Gene Symbol	Mesp2
Entrez Gene	17293
Alt Symbol	bHLHc6
Species	Mouse
Gene Type	protein-coding
Description	mesoderm posterior 2
Other Description	mesoderm posterior protein 2
Swissprots	Q3UIV5 O08574
Accessions	EDL07045 O08574 AK146740 BAE27401 BC145652 AAI45653 BC145654 AAI45655 U71125 AAB51199 NM_008589 NP_032615
Function	Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. May play a role with Tcf15 in the differentiation of myotomal and sclerotomal cells by regulating Pax family genes. Controls also the expression of the protocadherin PCDH8/PAPC, EPHA4, RIPPLY2, NOTCH2, FGFR1, and CER1. Binds to the E-boxes within the EPH4A and RIPPLY2 enhancers. {ECO:0000269\|PubMed:10887078, ECO:0000269\|PubMe
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00981, ECO:0000269\|PubMed:15902259, ECO:0000269\|PubMed:16996494}.

Anti-MESP2 Antibody (aa2-125) - LS-C308953 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-MESP2 Antibody (aa299-348) - LS-C30882 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (clone 1B3F9) - LS-C169154 from LifeSpan Bioscience

Prices	$365.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1B3F9

Western blot using MESP2 monoclonal antibody against HEK293 (1) and MESP2 (AA: 37-94)-hIgGFc transfected HEK293 (2) cell lysate.

MESP2 Antibody - NBP1-80219 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: MESP2 Antibody [NBP1-80219] - SP2/0 cell lysate, concentration 1.25ug/ml.

Anti-MESP2 antibody produced in rabbit - AV36921 from Sigma-Aldrich

Prices	$267.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: SP2/0 (<B>Cat. No. AV36921</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type SP2/0

MESP2 antibody - C-terminal region (ARP36921_T100) - ARP36921_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

MESP2 antibody - 20R-1126 from Fitzgerald

Prices	$290.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

MESP2 Antibody - 28-589 from ProSci

Prices	$250.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Antibody used in WB on Mouse SP2/0 at 1.25 ug/ml.

MESP2 Antibody - GWB-B3C6FF from Genway Biotech

Prices	$294.00
Sizes	100 µg
Clonality	Polyclonal

MESP2, Polyclonal Antibody - MBS834362 from MyBioSource

Prices	$390.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (Internal) - LS-C354418 from LifeSpan Bioscience

Prices	$245.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of MESP2 expression in A549 (A); NS-1 (B); H9C2 (C) whole cell lysates.

MESP2 antibody - TA341794 from Acris Antibodies

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

WB Suggested Anti-MESP2 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: SP2/0 cell lysate

MESP2 antibody - C-terminal region : Biotin (ARP36921_T100-Biotin) - ARP36921_T100-Biotin from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

MESP2 antibody - C-terminal region : FITC (ARP36921_T100-FITC) - ARP36921_T100-FITC from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

MESP2 antibody - C-terminal region : HRP (ARP36921_T100-HRP) - ARP36921_T100-HRP from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody A07046 - A07046 from Boster Bio

Prices	$299.00
Sizes	1
Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (FITC) - LS-C533059 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-MESP2 Antibody (HRP) - LS-C543145 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-MESP2 Antibody (aa299-348, HRP) - LS-C434931 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (APC) - LS-C514800 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-MESP2 Antibody (Biotin) - LS-C523015 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-MESP2 Antibody (aa299-348, FITC) - LS-C434929 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (aa299-348, Biotin) - LS-C434930 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody - LS-C497060 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-MESP2 Antibody (AP) - LS-C505090 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

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