PDHA1

Gene Symbol	PDHA1
Entrez Gene	5160
Alt Symbol	PDHA, PDHAD, PDHCE1A, PHE1A
Species	Human
Gene Type	protein-coding
Description	pyruvate dehydrogenase (lipoamide) alpha 1
Other Description	PDHE1-A type I|pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial|pyruvate dehydrogenase complex, E1-alpha polypeptide 1
Swissprots	Q53H41 B7Z3T7 A5YVE9 Q9NP12 Q9UBJ8 Q5JPT8 Q9UNG5 Q9UBU0 P08559 Q9UNG4 B7Z3X5 B2R5P7
Accessions	AAA31853 AAA60051 AAB32351 AAB39723 AAB39724 AAB39725 AAB39726 AAB39727 AAB39728 AAB39729 AAB39730 AAD16047 AAD23841 AAD23842 AAD23843 AAD23844 AAD23845 AAD23846 AAD23847 AAD23848 AAD23849 AAD23850 AAD23851 AAD23852 AAD23853 AAD23854 AAD23855 AAD23856 AAD23857 AAD23858 AAD23859 AAD23860 AAD23861 AAD23862 AAD23863 AAD23864 AAD23866 AAD23867 AAD23868 AAD23869 AAD23870 AAD23871 AAD23872 AAD23873 AAD23874 AAD23875 AAD23876 BAA14121 EAW98960 EAW98961 P08559 AK129887 AK222740 BAD96460 AK222988 BAD96708 AK293250 BAH11476 AK296341 BAH12323 AK296457 BAH12361 AK312263 BAG35194 AW204705 BC002406 AAH02406 BU170389 DA075402 DC361191 DQ891865 ABM82791 DQ895054 ABM85980 DQ895057 ABM85983 EF576990 ABQ58815 EF590116 EF590117 ABQ59099 J03503 AAA60055 J03575 AAA60050 L13318 AAA60227 L48690 AAB59581 M24848 AAA36533 R49470 S89908 AAB21863 X52709 CAA36933 X52710 CAA36934 XM_011545531 XP_011543833 XM_011545532 XP_011543834 NM_000284 NP_000275 NM_001173454 NP_001166925 NM_001173455 NP_001166926 NM_001173456 NP_001166927
Function	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. {ECO:0000269|PubMed:19081061, ECO:0000269|PubMed:7782287}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Ubiquitous.
Top Pathways	Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Central carbon metabolism in cancer, Glucagon signaling pathway, Pyruvate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDHA1-Over-expression-Lysate - LY10693a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PDHA1 293T Cell Transient Overexpression Lysate(Denatured) - H00005160-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PDHA1 overexpression lysate - LY432934 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PDHA1 overexpression lysate - LY432995 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PDHA1 overexpression lysate - LY433066 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PDHA1 293 Cell Lysate - 400195 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Pyruvate Dehydrogenase E1-alpha subunit Overexpression Lysate (Denatured) - H00005160-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Pyruvate Dehydrogenase E1-alpha subunit Overexpression Lysate (Native) - NBL1-14241 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PDH-E1α (h3): 293T Lysate`` - sc-159233 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

PDHA1 Over-expression Lysate Product - GWB-ADDB6B from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human PDHA1 / C54G1 (aa 30-390) Insect Cell Lysate (WB positive control) - 14567-HNCBL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PDHA1 / C54G1 (aa 30-390) Insect Cell Lysate (WB positive control) - 14567-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PDHA1 (aa 30-390) Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175601 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human PDHA1 (aa 30-390) Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175602 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

PDHA1-knockout Cell lysate - LC810167 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human PDHA1 Knockdown Stable Cell Line - CSC-DC011527 from Creative biogene Category Cell Line Species Human

Human PDHA1 Knockout Cell Line-HeLa - CSC-RT0591 from Creative biogene Category Cell Line Species Human

PDHA1 KO Cell Lysate-HeLa - CLKO-0096 from Creative biogene Category Cell Lysate

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