ATF1

Gene Symbol ATF1
Entrez Gene 466
Alt Symbol EWS-ATF1, FUS/ATF-1, TREB36
Species Human
Gene Type protein-coding
Description activating transcription factor 1
Other Description cAMP-dependent transcription factor ATF-1|cyclic AMP-dependent transcription factor ATF-1
Swissprots P25168 P18846 B4DRF9
Accessions AAB25878 CAA39150 EAW58151 P18846 AK299240 BAG61271 AK313406 BAG36201 BC029619 AAH29619 BG502726 BG545632 BG611151 BG611861 BI712653 BU682151 BX102171 DA468394 EU446464 ABZ91993 EU446626 ABZ92155 XM_011538386 XP_011536688 XM_011538387 XP_011536689 XM_011538388 XP_011536690 NM_005171 NP_005162
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. {ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:20980392}.
Subcellular Location Nucleus.
Top Pathways HTLV-I infection, Transcriptional misregulation in cancer

ATF-1 (25C10G) - sc-270 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATF-1 (25C10G): sc-270. Immunofluorescence staining of methanol-fixed HeLa cells (A) and immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor (B) showing nuclear localization.

ATF-1 (C41-5.1) - sc-243 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATF-1 (C41-5.1): sc-243. Western blot analysis of ATF-1 p35 expression in A-431 cells at antibody dilutions of 1.0 µg/ml (A) and 0.1 µg/ml (B).

ATF-1 (H-3) - sc-365525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATF-1 (H-3): sc-365525. Western blot analysis of ATF-1 expression in Jurkat (A) and HeLa (B) nuclear extracts.

ATF-1 (ATF1 2A9/8) - sc-53172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATF-1 (ATF1 2A9/8): sc-53172. Western blot analysis of human recombinant ATF-1

ATF-1 (H-60) - sc-28673 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ATF-1 (H-60): sc-28673. Western blot analysis of ATF-1 expression in HeLa nuclear extract.

ATF-1 (FI-1) - sc-241 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATF-1 (FI-1): sc-241. Western blot analysis of human recombinant ATF-1.

CREB-1 (D-4) - sc-374227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB-1 (D-4): sc-374227. Western blot analysis of CREB-1 expression in non-transfected: sc-117752 (A) and mouse CREB-1 transfected: sc-119446 (B) 293T whole cell lysates.

CREB-1 (C-21) - sc-186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB-1 (C-21): sc-186. Western blot analysis of CREB-1 expression in non-transfected: sc-110760 (A) and human CREB-1 transfected: sc-111160 (B) 293 whole cell lysates.

Anti-ATF1 (phospho S63) antibody - ab138359 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ATF1 (phospho S63) antibody (ab138359) at 1/500 dilution + HT29 cell extract treated with Insulin 0.01U/ML for 15 min at 30 µg

Anti-ATF1 (phospho S63) antibody [EP1591(2)Y] - ab76085 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1591(2)Y
All lanes : Anti-ATF1 (phospho S63) antibody [EP1591(2)Y] (ab76085) at 1/100000 dilutionLane 1 : HeLa cell lysate (untreated)Lane 2 : HeLa cell lysate, treated with Lambda PhosphataseLysates/proteins at 10 µg per lane.Secondarygoat anit rabbit HRP labelled IgG at 1/2000 dilution

Anti-ATF1 antibody - ab189311 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin labeling ATF1 with ab189311 at 10 µg/ml

Anti-ATF1 antibody - ab78903 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ATF1 antibody (ab78903) at 1/500 dilutionLane 1 : COLO cell extractLane 2 : COLO cell extract with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-ATF1 antibody - ab66016 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ATF1 antibody (ab66016) at 1/500 dilutionLane 1 : COLO205 cell extractsLane 2 : HeLa cell extractsLane 3 : HepG2 cell extractsLane 4 : HepG2 cell extracts with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-ATF1 antibody - ab110869 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of ATF1 by Western Blot of Immunprecipitate. anti-ATF1 at 0.4µg/ml staining ATF1 in HeLa whole cell lysate immunoprecipitated using ab110869 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-ATF1 antibody - ab11830 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ATF1 antibody [ATF1 2A9/8] - ab36374 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ATF1 2A9/8

Anti-ATF1 antibody [EPR1590(2)] - ab134104 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1590(2)
All lanes : Anti-ATF1 antibody [EPR1590(2)] (ab134104) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ATF1 Antibody (aa1-271) - LS-C343989 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ATF1 antibody IHC-paraffin: Human Intestinal Cancer Tissue.

Anti-ATF1 Antibody - LS-C63598 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ATF1 Antibody (aa31-80) - LS-C117593 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO cells, using ATF1 (Ab-63) Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ATF1 Antibody (C-Terminus, AP) - LS-C208053 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATF1 Antibody (Thr209) - LS-C176744 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of ATF1 (T209) pAb in extracts from HepG2 cells.

Anti-ATF1 Antibody (phospho-Ser63, clone EP1591(2)Y) - LS-C105416 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1591(2)Y
IHC of paraffin-embedded human breast carcinoma using Phospho-specific anti-ATF-1 antibody (LS-C105416).

Anti-ATF1 Antibody (C-Terminus, clone EPR1590(2)) - LS-C137983 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1590(2)
Western blot analysis on (A) K562, (B) HeLa, and (C) HepG2 cell lysates using anti-ATF-1 antibody.

Anti-ATF1 Antibody (C-Terminus, Biotin) - LS-C208055 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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