ATF1

Gene Symbol ATF1
Entrez Gene 466
Alt Symbol EWS-ATF1, FUS/ATF-1, TREB36
Species Human
Gene Type protein-coding
Description activating transcription factor 1
Other Description cAMP-dependent transcription factor ATF-1|cyclic AMP-dependent transcription factor ATF-1
Swissprots P25168 P18846 B4DRF9
Accessions AAB25878 CAA39150 EAW58151 P18846 AK299240 BAG61271 AK313406 BAG36201 BC029619 AAH29619 BG502726 BG545632 BG611151 BG611861 BI712653 BU682151 BX102171 DA468394 EU446464 ABZ91993 EU446626 ABZ92155 XM_011538386 XP_011536688 XM_011538387 XP_011536689 XM_011538388 XP_011536690 NM_005171 NP_005162
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. {ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:20980392}.
Subcellular Location Nucleus.
Top Pathways HTLV-I infection, Transcriptional misregulation in cancer

ATF-1 CRISPR/Cas9 KO Plasmid (h) - sc-400488 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 HDR Plasmid (h) - sc-400488-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 Double Nickase Plasmid (h) - sc-400488-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 Double Nickase Plasmid (h2) - sc-400488-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 CRISPR Activation Plasmid (h) - sc-400488-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 CRISPR Activation Plasmid (h2) - sc-400488-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 Lentiviral Activation Particles (h) - sc-400488-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 Lentiviral Activation Particles (h2) - sc-400488-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATF-1 siRNA (h) - sc-29754 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF-1 shRNA Plasmid (h) - sc-29754-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF-1 shRNA (h) Lentiviral Particles - sc-29754-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATF1 RNAi - H00000466-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ATF1 RNAi - H00000466-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU006361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3633 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3633 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATF1 siRNA (Human) - CRH0324 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATF1 - MBS8239827 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATF1 (NM_005171.4) - SHH241894 from Creative biogene

Category siRNA
Species Reactivities Human

ATF1 shRNA Plasmid (Human) - CHH0324 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATF1 miRNA 3'UTR clone - MiUTR3H-00558 from Creative biogene

Species Reactivities Human
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