MYO1G

Gene Symbol	MYO1G
Entrez Gene	64005
Alt Symbol	HA2, HLA-HA2, MHAG
Species	Human
Gene Type	protein-coding
Description	myosin IG
Other Description	minor histocompatibility antigen HA-2|myosin-Ig|unconventional myosin-Ig
Swissprots	Q96RI5 Q96BE2 Q96RI6 Q8TES2 Q8TEI9 B0I1T2
Accessions	B0I1T2 EAL23748 EAW61068 EAW61069 EAW61070 EAW61071 EAW61072 AA651942 AB290179 BAG06733 AF380932 AAK58092 AF380933 AAK58093 AK074050 BAB84876 AK074135 BAB84961 AK097912 BAG53548 AK131089 BAC85139 AL832302 BC007370 BC015693 AAH15693 BC031337 BC041623 BC063854 BC113544 AAI13545 BC117241 AAI17242 BI910371 DB131347 XR_926942 XR_926943 NM_033054 NP_149043
Function	Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T- cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B- cells, where it regulates different membrane/cytoskeleton- dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis. {ECO:0000250|UniProtKB:Q5SUA5}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19968988, ECO:0000269|PubMed:20071333}; Peripheral membrane protein {ECO:0000269|PubMed:19968988, ECO:0000269|PubMed:20071333}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:Q5SUA5}. Note=Recruited to Fc-gamma receptor (Fc-gamma-R) phagocytic cup. In T-cells, transiently accumulates in discrete areas at the plasma membrane of migrating cells or when membranes are deformed (By similarity). Localization at the membrane is not highly dependent on phosphatidylinositol 4,5-bisphosphate levels. Released from the membrane in the presence of ATP. May be enriched in peripheral processes, such as microvilli or ruffles. {ECO:0000250|UniProtKB:Q5SUA5, ECO:0000269|PubMed:20071333}.
Tissue Specificity	Specifically expressed in hematopoietic cells. {ECO:0000269|PubMed:11544309, ECO:0000269|PubMed:20071333}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Influenza B HA2 Fc tag protein - orb84619 from Biorbyt Category Protein Prices $536.00, $808.00 Sizes 50 μg, 100 μg Source Human

H5N1 HA2 Fc tag protein - orb84616 from Biorbyt Category Protein Prices $417.00, $595.00 Sizes 50 μg, 100 μg Source Human

Influenza B HA2 Fc tag protein - orb84618 from Biorbyt Category Protein Prices $417.00, $595.00 Sizes 50 μg, 100 μg Source Human

Human Myosin IG Protein - abx068163 from Abbexa Category Protein Source E.coli Species Human

Myosin IG (MYO1G), Human - 20-8792 from ARP American Research Products Category Protein Prices $537.00 Sizes 50 µg Source E.coli Species Human

MYO1G fusion protein - Ag22696 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET28a Species Human

Recombinant Human MYO1G - MYO1G-1188H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Myosin IG (MYO1G) - RPD436Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Myosin IG (MYO1G) - RPD436Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Myosin IG (MYO1G) - RPD436Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Unconventional myosin-Ig(MYO1G) ,partial - CSB-YP015344HU CSB-EP015344HU CSB-BP015344HU CSB-MP015344HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Myosin IG (MYO1G) - RPU142889 from Biomatik Category Protein Prices $257.40, $514.80, $772.20 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

MYO1G Recombinant Protein Antigen - NBP1-93704PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MYO1G Peptide, Human - M34GP10029H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Myosin IG (MYO1G) - RPU42889 from Biomatik Category Protein Prices $206.00, $402.00, $644.00, $767.52 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

MYO1G Recombinant Protein (OPCD05546) - OPCD05546 from Aviva Systems Biology Category Protein Source E.coli Species Human

Myosin IG, Recombinant Protein - MBS2029158 from MyBioSource Category Protein Prices $190.00, $395.00, $610.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Myosin IG (MYO1G), Recombinant Protein - MBS2009284 from MyBioSource Category Protein Prices $195.00, $420.00, $645.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

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