Gene Symbol | ASXL2 |
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Entrez Gene | 55252 |
Alt Symbol | ASXH2 |
Species | Human |
Gene Type | protein-coding |
Description | additional sex combs like transcriptional regulator 2 |
Other Description | additional sex combs like 2|additional sex combs-like protein 2|polycomb group protein ASXH2|putative Polycomb group protein ASXL2 |
Swissprots | Q5H9U4 Q76L83 Q9NV67 Q53TC9 Q76L81 Q9C0H8 Q86XM1 |
Accessions | AAY14841 EAX00716 EAX00717 Q76L83 AB051472 BAB21776 AB084279 BAD00086 AK000649 AK001760 BAA91889 BC042999 AAH42999 BX647527 BX648218 CR933613 CAI45930 JF432409 ADZ15626 XM_006712039 XP_006712102 XM_006712040 XP_006712103 XM_011532950 XP_011531252 XM_011532951 XP_011531253 NM_018263 NP_060733 |
Function | Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3. {ECO:0000250, ECO:0000269|PubMed:21047783}. |
Subcellular Location | Nucleus {ECO:0000305}. |
ASXL2 (V-17) - sc-169972 from Santa Cruz Biotechnology
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Anti-ASXL2 antibody - ab176599 from Abcam
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Anti-ASXL2 antibody - ab69420 from Abcam
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Anti-ASXL2 antibody - ab106540 from Abcam
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Anti-ASXL2 antibody [7A11] - ab154984 from Abcam
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Anti-ASXL2 Antibody (aa600-650) - LS-C288792 from LifeSpan Bioscience
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Anti-ASXL2 Antibody - LS-C309535 from LifeSpan Bioscience
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Anti-ASXL2 Antibody - LS-C306417 from LifeSpan Bioscience
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Anti-ASXL2 Antibody (aa575-624) - LS-C111996 from LifeSpan Bioscience
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ASXL2 Antibody - NBP1-56576 from Novus Biologicals
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ASXL2 Antibody - NBP1-18926 from Novus Biologicals
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ASXL2 Antibody - H00055252-B01P from Novus Biologicals
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ASXL2 Antibody - H00055252-D01 from Novus Biologicals
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Anti-ASXL2 antibody produced in rabbit - SAB2106066 from Sigma-Aldrich
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Anti-ASXL2 antibody produced in mouse - SAB1407639 from Sigma-Aldrich
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ASXL2 antibody - middle region (ARP57184_P050) - ARP57184_P050 from Aviva Systems Biology
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ASXL2 antibody, Internal - GTX44956 from GeneTex
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Anti -ASXL2 (Putative Polycomb Group Protein ASXL2, Additional Sex Combs-like Protein 2,ASXH2, KIAA1685, DKFZp686C1968, FLJ10898) - 123653 from USBiological Life Science
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Anti -ASXL2 (Putative Polycomb Group Protein ASXL2, Additional Sex Combs-like Protein 2,ASXH2, KIAA1685, DKFZp686C1968, FLJ10898) - 123654 from USBiological Life Science
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ASXL2 antibody - 70R-3526 from Fitzgerald
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ASXL2 Antibody - abx036875 from Abbexa
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ASXL2 antibody - H00055252-B01P from Acris Antibodies
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ASXL2 antibody - H00055252-D01 from Acris Antibodies
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ASXL2 Antibody - E220122-1 from Enogene
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ASXL2 Antibody - E220122-2 from Enogene
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