ASXL2

Gene Symbol ASXL2
Entrez Gene 55252
Alt Symbol ASXH2
Species Human
Gene Type protein-coding
Description additional sex combs like transcriptional regulator 2
Other Description additional sex combs like 2|additional sex combs-like protein 2|polycomb group protein ASXH2|putative Polycomb group protein ASXL2
Swissprots Q5H9U4 Q76L83 Q9NV67 Q53TC9 Q76L81 Q9C0H8 Q86XM1
Accessions AAY14841 EAX00716 EAX00717 Q76L83 AB051472 BAB21776 AB084279 BAD00086 AK000649 AK001760 BAA91889 BC042999 AAH42999 BX647527 BX648218 CR933613 CAI45930 JF432409 ADZ15626 XM_006712039 XP_006712102 XM_006712040 XP_006712103 XM_011532950 XP_011531252 XM_011532951 XP_011531253 NM_018263 NP_060733
Function Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3. {ECO:0000250, ECO:0000269|PubMed:21047783}.
Subcellular Location Nucleus {ECO:0000305}.

ASXL2 CRISPR/Cas9 KO Plasmid (h) - sc-406695 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 HDR Plasmid (h) - sc-406695-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 Double Nickase Plasmid (h) - sc-406695-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 Double Nickase Plasmid (h2) - sc-406695-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 CRISPR Activation Plasmid (h) - sc-406695-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 CRISPR Activation Plasmid (h2) - sc-406695-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 Lentiviral Activation Particles (h) - sc-406695-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 Lentiviral Activation Particles (h2) - sc-406695-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 siRNA (h) - sc-94416 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASXL2 shRNA Plasmid (h) - sc-94416-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASXL2 shRNA (h) Lentiviral Particles - sc-94416-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU081391 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3620 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3620 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11666 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11666

ASXL2 siRNA (Human) - CRJ0597 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASXL2 - MBS828739 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASXL2 CRISPR/Cas9 KO Plasmid (h2) - sc-406695-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASXL2 HDR Plasmid (h2) - sc-406695-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human ASXL2 (NM_018263.4) - SHH241758 from Creative biogene

Category siRNA
Species Reactivities Human

Human ASXL2 siRNA - orb271098 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASXL2 shRNA Plasmid (Human) - CHJ0597 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ASXL2 miRNA 3'UTR clone - MiUTR1H-00649 from Creative biogene

Species Reactivities Human
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