ASXL2

Gene Symbol	ASXL2
Entrez Gene	55252
Alt Symbol	ASXH2
Species	Human
Gene Type	protein-coding
Description	additional sex combs like transcriptional regulator 2
Other Description	additional sex combs like 2|additional sex combs-like protein 2|polycomb group protein ASXH2|putative Polycomb group protein ASXL2
Swissprots	Q5H9U4 Q76L83 Q9NV67 Q53TC9 Q76L81 Q9C0H8 Q86XM1
Accessions	AAY14841 EAX00716 EAX00717 Q76L83 AB051472 BAB21776 AB084279 BAD00086 AK000649 AK001760 BAA91889 BC042999 AAH42999 BX647527 BX648218 CR933613 CAI45930 JF432409 ADZ15626 XM_006712039 XP_006712102 XM_006712040 XP_006712103 XM_011532950 XP_011531252 XM_011532951 XP_011531253 NM_018263 NP_060733
Function	Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3. {ECO:0000250, ECO:0000269|PubMed:21047783}.
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ASXL2 Antibody Blocking Peptide - LS-E20863 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ASXL2 Blocking Peptide - 33R-2337 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ASXL2 fusion protein - ag6272 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Putative Polycomb group protein ASXL2(ASXL2) ,partial - CSB-YP765736HU CSB-EP765736HU CSB-BP765736HU CSB-MP765736HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HAT-3, Peptide - MBS843880 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

MOZ/KAT6A, Peptide - MBS425615 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

ASXL2 Peptide, Human - M34GP01070H from Creative Peptides Category Peptide Source Synthetic. Species Human

ASXL2 Recombinant Protein Antigen - NBP2-58342PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ASXL2 Recombinant Protein Antigen - NBP2-56782PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Putative Polycomb group protein ASXL2 (ASXL2), partial, Recombinant Protein - MBS1441134 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ASXL2 fusion protein - Ag24402 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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