Gene Symbol | ZRSR2 |
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Entrez Gene | 8233 |
Alt Symbol | U2AF1-RS2, U2AF1L2, U2AF1RS2, URP |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 |
Other Description | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2|U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2|U2(RNU2) small nuclear RNA auxiliary factor 1-like 2|U2AF35-related protein|renal carcinoma antigen NY-REN-20 |
Swissprots | Q14D69 Q15696 |
Accessions | EAW98900 EAW98901 EAW98902 Q15696 AK090845 AK309673 BC050451 AAH50451 BC065719 BC113454 AAI13455 BC113480 AAI13481 D49677 BAA08533 HQ258575 ADR83329 XM_005274597 XP_005274654 XM_006724519 XP_006724582 XM_011545589 XP_011543891 XM_011545590 XP_011543892 NM_005089 NP_005080 |
Function | Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP- dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing. {ECO:0000269|PubMed:21041408, ECO:0000269|PubMed:9237760}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15146077}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9237760}. |
ZRSR2 (J-17) - sc-130001 from Santa Cruz Biotechnology
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Anti-ZRSR2 antibody - ab50753 from Abcam
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Anti-ZRSR2 antibody - ab94591 from Abcam
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Anti-ZRSR2 antibody - C-terminal - ab180212 from Abcam
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Anti-ZRSR2 Antibody (aa107-156) - LS-C110538 from LifeSpan Bioscience
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Anti-ZRSR2 Antibody (clone 2H5) - LS-C198538 from LifeSpan Bioscience
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Anti-ZRSR2 Antibody (aa369-418) - LS-C31154 from LifeSpan Bioscience
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Anti-ZRSR2 Antibody (aa453-482) - LS-C203992 from LifeSpan Bioscience
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ZRSR2 Antibody - NBP1-57317 from Novus Biologicals
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ZRSR2 Antibody - NBP1-57307 from Novus Biologicals
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ZRSR2 Antibody - H00008233-B01P from Novus Biologicals
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ZRSR2 Antibody (2H5) - H00008233-M03 from Novus Biologicals
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Anti-ZRSR2, (N-terminal) antibody produced in rabbit - SAB2104500 from Sigma-Aldrich
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Anti-ZRSR2 antibody produced in rabbit - AV40573 from Sigma-Aldrich
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ZRSR2 antibody - C-terminal region (ARP40573_T100) - ARP40573_T100 from Aviva Systems Biology
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ZRSR2 antibody - N-terminal region (ARP40574_P050) - ARP40574_P050 from Aviva Systems Biology
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ZRSR2-Antibody-C-term - AP20436b from Abgent, a WuXi AppTec company
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ZRSR2-Antibody-C-term - AW5111 from Abgent, a WuXi AppTec company
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ZRSR2 Antibody - C-terminal region (OAAB17961) - OAAB17961 from Aviva Systems Biology
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ZRSR2 antibody - 70R-4763 from Fitzgerald
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ZRSR2 Antibody - abx034802 from Abbexa
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ZRSR2 antibody - AP42736PU-N from Acris Antibodies
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ZRSR2 antibody - H00008233-B01P from Acris Antibodies
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ZRSR2 antibody - H00008233-M03 from Acris Antibodies
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Rabbit Anti-Human ZRSR2 (C-term) - 102-14778 from RayBiotech
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