BRIP1

Gene Symbol	BRIP1
Entrez Gene	83990
Alt Symbol	BACH1, FANCJ, OF
Species	Human
Gene Type	protein-coding
Description	BRCA1 interacting protein C-terminal helicase 1
Other Description	ATP-dependent RNA helicase BRIP1|BRCA1-associated C-terminal helicase 1|BRCA1-binding helicase-like protein BACH1|BRCA1/BRCA2-associated helicase 1|Fanconi anemia group J protein
Swissprots	Q8NCI5 Q9BX63 Q3MJE2
Accessions	EAW51430 EAW51431 EAW51432 EAW51433 Q9BX63 AF360549 AAK38111 AK074713 BAC11156 BC101472 AAI01473 BC101474 AAI01475 HQ258538 ADR83292 XM_011525332 XP_011523634 XM_011525333 XP_011523635 XM_011525334 XP_011523636 XM_011525335 XP_011523637 XM_011525336 XP_011523638 XM_011525337 XP_011523639 XM_011525338 XP_011523640 XM_011525339 XP_011523641 XM_011525340 XP_011523642 XM_011525341 XP_011523643 NM_032043 NP_114432
Function	DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. {ECO:0000269|PubMed:11301010, ECO:0000269|PubMed:14983014, ECO:0000269|PubMed:16116421, ECO:0000269|PubMed:16153896}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11301010}.
Tissue Specificity	Ubiquitously expressed, with highest levels in testis. {ECO:0000269|PubMed:11301010}.
Top Pathways	Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BACH1 Antibody Blocking Peptide - LS-E3473 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRIP1 / BACH1 Antibody Blocking Peptide - LS-E387 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRIP1 / BACH1 Antibody Blocking Peptide - LS-E24337 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BACH1 Partial Recombinant Protein - H00000571-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

BRIP1-Antibody-N-term-Blocking-peptide - BP10665a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BACH1 Blocking Peptide - abx062283 from Abbexa Category Peptide Species Human, Monkey

BRIP1 fusion protein - Ag19907 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BRIP1 fusion protein - ag19450 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human BRIP1, His-tagged - BRIP1-10291H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Fanconi anemia group J protein(BRIP1) ,partial - CSB-YP866300HU CSB-EP866300HU CSB-BP866300HU CSB-MP866300HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BACH1 Protein - abx164864 from Abbexa Category Protein Species Human

BRIP1/FANCJ Recombinant Protein Antigen - NBP2-14361PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BACH1 Protein - NBP1-88722PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

BACH1 Peptide, Human - M34GP01293H from Creative Peptides Category Peptide Source Synthetic. Species Human

BRIP1 Peptide, Human - M34GP01538H from Creative Peptides Category Peptide Source Synthetic. Species Human

Fanconi anemia group J protein (BRIP1), partial, Recombinant Protein - MBS1358544 from MyBioSource Category Protein Prices $555.00, $715.00, $745.00, $820.00, $865.00, $965.00, $1,085.00, $1,090.00, $1,105.00, $1,150.00, $1,580.00, $1,645.00, $1,685.00, $2,115.00 Sizes 50 µg (E-Coli), 50 µg (Yeast), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 200 µg (Yeast), 500 µg (Yeast), 100 µg (Baculovirus), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 500 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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