BRIP1

Gene Symbol BRIP1
Entrez Gene 83990
Alt Symbol BACH1, FANCJ, OF
Species Human
Gene Type protein-coding
Description BRCA1 interacting protein C-terminal helicase 1
Other Description ATP-dependent RNA helicase BRIP1|BRCA1-associated C-terminal helicase 1|BRCA1-binding helicase-like protein BACH1|BRCA1/BRCA2-associated helicase 1|Fanconi anemia group J protein
Swissprots Q8NCI5 Q9BX63 Q3MJE2
Accessions EAW51430 EAW51431 EAW51432 EAW51433 Q9BX63 AF360549 AAK38111 AK074713 BAC11156 BC101472 AAI01473 BC101474 AAI01475 HQ258538 ADR83292 XM_011525332 XP_011523634 XM_011525333 XP_011523635 XM_011525334 XP_011523636 XM_011525335 XP_011523637 XM_011525336 XP_011523638 XM_011525337 XP_011523639 XM_011525338 XP_011523640 XM_011525339 XP_011523641 XM_011525340 XP_011523642 XM_011525341 XP_011523643 NM_032043 NP_114432
Function DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. {ECO:0000269|PubMed:11301010, ECO:0000269|PubMed:14983014, ECO:0000269|PubMed:16116421, ECO:0000269|PubMed:16153896}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11301010}.
Tissue Specificity Ubiquitously expressed, with highest levels in testis. {ECO:0000269|PubMed:11301010}.
Top Pathways Fanconi anemia pathway

BRIP1 CRISPR/Cas9 KO Plasmid (h) - sc-407632 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 HDR Plasmid (h) - sc-407632-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 Double Nickase Plasmid (h) - sc-407632-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 Double Nickase Plasmid (h2) - sc-407632-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 CRISPR Activation Plasmid (h) - sc-407632-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 CRISPR Activation Plasmid (h2) - sc-407632-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 Lentiviral Activation Particles (h) - sc-407632-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 Lentiviral Activation Particles (h2) - sc-407632-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRIP1 siRNA (h) - sc-43640 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRIP1 shRNA Plasmid (h) - sc-43640-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRIP1 shRNA (h) Lentiviral Particles - sc-43640-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BACH1 RNAi - H00000571-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BRIP1/FANCJ RNAi - H00083990-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BACH1 RNAi - H00000571-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1226 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1226 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BRIP1 siRNA (Human) - CRJ3261 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRIP1 - MBS8224966 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BRIP1 (NM_032043.2) - SHH247742 from Creative biogene

Category siRNA
Species Reactivities Human

Human BRIP1 siRNA - orb273762 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRIP1 shRNA Plasmid (Human) - CHJ3261 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BRIP1 miRNA 3'UTR clone - MiUTR3H-08017 from Creative biogene

Species Reactivities Human
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