Gene Symbol | CLDN10 |
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Entrez Gene | 9071 |
Alt Symbol | CPETRL3, OSP-L |
Species | Human |
Gene Type | protein-coding |
Description | claudin 10 |
Other Description | OSP-like protein|claudin-10 |
Swissprots | Q96N78 Q6IBF9 P78369 |
Accessions | EAX08955 P78369 AF339794 AK055855 BAB71030 AK315737 BAG38092 BC010920 AAH10920 BG697724 BU930613 CR456845 CAG33126 DA133712 DA636757 DB544708 DQ892831 ABM83757 DQ896077 ABM87076 U89916 AAC79506 XM_011521134 XP_011519436 NM_001160100 NP_001153572 NM_006984 NP_008915 NM_182848 NP_878268 |
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney. {ECO:0000269|PubMed:19383724}. |
Subcellular Location | Cell junction, tight junction {ECO:0000269|PubMed:19383724}. Cell membrane {ECO:0000269|PubMed:19383724}; Multi-pass membrane protein {ECO:0000269|PubMed:19383724}. |
Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |
claudin-10 (G-12) - sc-373946 from Santa Cruz Biotechnology
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claudin-10 (H-10) - sc-373700 from Santa Cruz Biotechnology
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claudin-10 (F-20) - sc-17678 from Santa Cruz Biotechnology
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claudin-10 (H-58) - sc-25710 from Santa Cruz Biotechnology
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claudin-10 (K-18) - sc-17675 from Santa Cruz Biotechnology
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Anti-Claudin 10 antibody - ab66053 from Abcam
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Anti-Claudin 10 antibody - ab52234 from Abcam
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Anti-Claudin 10 antibody - ab24792 from Abcam
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Anti-Claudin 10 antibody - ab49423 from Abcam
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Anti-Claudin 10 antibody, prediluted - ab53637 from Abcam
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Anti-CLDN10 / Claudin 10 Antibody (C-Terminus) - LS-C6166 from LifeSpan Bioscience
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Anti-CLDN10 / Claudin 10 Antibody (N-Terminus) - LS-C30634 from LifeSpan Bioscience
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Anti-CLDN10 / Claudin 10 Antibody (C-Terminus) IHC-plus™ - LS-B5184 from LifeSpan Bioscience
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Anti-CLDN10 / Claudin 10 Antibody (aa179-228) - LS-C118410 from LifeSpan Bioscience
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Anti-CLDN10 / Claudin 10 Antibody (Asn217) - LS-C175964 from LifeSpan Bioscience
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Claudin-10b Antibody (394513) - MAB4279 from Novus Biologicals
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Claudin 10 Antibody - NBP1-35655 from Novus Biologicals
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Claudin 10 Antibody - NBP1-67523 from Novus Biologicals
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Claudin 10 Antibody - NB100-91708 from Novus Biologicals
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Claudin 10 Antibody - NBP2-38495 from Novus Biologicals
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Claudin 10 Antibody - H00009071-B01P from Novus Biologicals
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Claudin 10 Polyclonal Antibody - bs-13739R from Bioss
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Claudin 10 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13739R-A350 from Bioss
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Claudin 10 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13739R-A488 from Bioss
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Claudin 10 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13739R-A555 from Bioss
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