CLDN10

Gene Symbol	CLDN10
Entrez Gene	9071
Alt Symbol	CPETRL3, OSP-L
Species	Human
Gene Type	protein-coding
Description	claudin 10
Other Description	OSP-like protein|claudin-10
Swissprots	Q96N78 Q6IBF9 P78369
Accessions	EAX08955 P78369 AF339794 AK055855 BAB71030 AK315737 BAG38092 BC010920 AAH10920 BG697724 BU930613 CR456845 CAG33126 DA133712 DA636757 DB544708 DQ892831 ABM83757 DQ896077 ABM87076 U89916 AAC79506 XM_011521134 XP_011519436 NM_001160100 NP_001153572 NM_006984 NP_008915 NM_182848 NP_878268
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney. {ECO:0000269|PubMed:19383724}.
Subcellular Location	Cell junction, tight junction {ECO:0000269|PubMed:19383724}. Cell membrane {ECO:0000269|PubMed:19383724}; Multi-pass membrane protein {ECO:0000269|PubMed:19383724}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

claudin-10 CRISPR/Cas9 KO Plasmid (h) - sc-406781 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 HDR Plasmid (h) - sc-406781-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 Double Nickase Plasmid (h) - sc-406781-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 Double Nickase Plasmid (h2) - sc-406781-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 CRISPR Activation Plasmid (h) - sc-406781-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 CRISPR Activation Plasmid (h2) - sc-406781-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 Lentiviral Activation Particles (h) - sc-406781-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 Lentiviral Activation Particles (h2) - sc-406781-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

claudin-10 siRNA (h) - sc-43052 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

claudin-10 shRNA Plasmid (h) - sc-43052-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

claudin-10 shRNA (h) Lentiviral Particles - sc-43052-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Claudin 10 RNAi - H00009071-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Claudin 10 RNAi - H00009071-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU147351 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6172 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6172 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CLDN10 siRNA (Human) - CRH5988 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CLDN10 - MBS8213486 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CLDN10 (NM_182848.3) - SHH264633 from Creative biogene Category siRNA Species Reactivities Human

Human CLDN10 siRNA - orb266490 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CLDN10 shRNA Plasmid (Human) - CHH5988 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CLDN10 miRNA 3'UTR clone - MiUTR3H-14460 from Creative biogene Species Reactivities Human

CLDN10 miRNA 3'UTR clone - MiUTR3H-14461 from Creative biogene Species Reactivities Human

CLDN10 miRNA 3'UTR clone - MiUTR3H-14462 from Creative biogene Species Reactivities Human

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