GZMH

Gene Symbol GZMH
Entrez Gene 2999
Alt Symbol CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2
Species Human
Gene Type protein-coding
Description granzyme H (cathepsin G-like 2, protein h-CCPX)
Other Description cytotoxic T-lymphocyte proteinase|cytotoxic T-lymphocyte-associated serine esterase 1|cytotoxin serine protease-C|granzyme H
Swissprots G3V2C5 Q6XGZ0 Q6XGZ1 P20718
Accessions AAA03514 AAA74885 AAA76859 EAW66004 EAW66005 P20718 AW204493 AY232657 AAP70247 AY232658 AAP70248 BC027974 AAH27974 BQ054303 CD000418 DQ892068 ABM82994 DQ895261 ABM86187 M36118 AAA03248 XM_011536683 XP_011534985 NM_001270780 NP_001257709 NM_001270781 NP_001257710 NM_033423 NP_219491
Function Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. {ECO:0000269|PubMed:22156497, ECO:0000269|PubMed:23269243}.
Subcellular Location Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes.
Tissue Specificity Constituvely expressed in NK cells. {ECO:0000269|PubMed:23269243}.

granzyme H (H-54) - sc-292691 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

granzyme H (K-14) - sc-47026 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
granzyme H (K-14): sc-47026. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing cytoplasmic and membrane staining of cells in non-germinal centers.

granzyme H (T-21) - sc-133636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
granzyme H (T-21): sc-133636. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic localization.

Anti-GZMH antibody - ab58852 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GZMH antibody (ab58852) at 2.5 µg/ml + Jurkat Cell Lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50,000 - 1/100,000 dilution.

Anti-GZMH antibody - ab69876 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GZMH antibody (ab69876) at 1/500 dilutionLane 1 : Extracts from K562 cellsLane 2 : Extracts from K562 cells with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-GZMH antibody - ab89607 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GZMH antibody (ab89607) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-GZMH antibody [MM0319-10A39] - ab89299 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0319-10A39

Anti-GZMH / Granzyme H Antibody - LS-C308109 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GZMH / Granzyme H Antibody (C-Terminus) - LS-C345341 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of GZMH Antibody with human 786-0 Whole Cell lysate.

Anti-GZMH / Granzyme H Antibody (N-Terminus) - LS-C31913 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
GZMH / Granzyme H antibody LS-C31913 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-GZMH / Granzyme H Antibody (aa51-100) - LS-C119553 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using GRAH Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GZMH / Granzyme H Antibody (Gly75) - LS-C177052 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Granzyme H (G75) pAb in paraffin-embedded human pancreas tissue.

Granzyme H Antibody [Unconjugated] - AF1377 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Granzyme H was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using Goat Anti-Human Granzyme H Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1377) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Granzyme H Antibody - NBP1-86565 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Granzyme H Antibody - H00002999-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GZMH Antibody [H00002999-B01] - GZMH MaxPab polyclonal antibody. Western Blot analysis of GZMH expression in human spleen.

Granzyme H Antibody - H00002999-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Granzyme H Antibody [H00002999-B01P] - Analysis of GZMH expression in human spleen.

Granzyme H Antibody - H00002999-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Granzyme H Antibody [H00002999-B02P] - Analysis of GZMH expression in human spleen.

Granzyme H Antibody - H00002999-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GZMH Antibody [H00002999-B02] - GZMH MaxPab polyclonal antibody (B02), Lot # 07313WULz. Western Blot analysis of GZMH expression in human spleen.

Granzyme H Antibody - NBP2-16771 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Granzyme H Antibody [NBP2-16771] - Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE gel, diluted at 1:1000.

Granzyme H Antibody [Biotin] - BAF1377 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Granzyme D/B/E/N/G/F/H Antibody - bs-2579R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

Anti-GZMH antibody produced in mouse - SAB1405915 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GZMH: <B>Cat. No. SAB1405915</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~27.3 kDa using human colon lysate.

Anti-GZMH antibody produced in rabbit - HPA029200 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GZMH: <B>Cat. No. HPA029200</B>: Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of cells.

Anti-GZMH antibody produced in mouse - SAB1409168 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GZMH: <B>Cat. No. SAB1409168</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~27.3 kDa using human spleen lysate.

Anti-Granzyme B, N-Terminal antibody produced in rabbit - SAB4501359 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-Granzyme B, N-Terminal: <B>Cat. No. SAB4501359</B>: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-Granzyme B, N-Terminal antibody. Cells on the left were treated with the Anti-Granzyme B, N-Terminal antibody. Cells on the right (negative control) were treated with both Anti-Granzyme B, N-Terminal antibody and the synthesized immunogen peptide.
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