GZMH

Gene Symbol GZMH
Entrez Gene 2999
Alt Symbol CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2
Species Human
Gene Type protein-coding
Description granzyme H (cathepsin G-like 2, protein h-CCPX)
Other Description cytotoxic T-lymphocyte proteinase|cytotoxic T-lymphocyte-associated serine esterase 1|cytotoxin serine protease-C|granzyme H
Swissprots G3V2C5 Q6XGZ0 Q6XGZ1 P20718
Accessions AAA03514 AAA74885 AAA76859 EAW66004 EAW66005 P20718 AW204493 AY232657 AAP70247 AY232658 AAP70248 BC027974 AAH27974 BQ054303 CD000418 DQ892068 ABM82994 DQ895261 ABM86187 M36118 AAA03248 XM_011536683 XP_011534985 NM_001270780 NP_001257709 NM_001270781 NP_001257710 NM_033423 NP_219491
Function Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. {ECO:0000269|PubMed:22156497, ECO:0000269|PubMed:23269243}.
Subcellular Location Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes.
Tissue Specificity Constituvely expressed in NK cells. {ECO:0000269|PubMed:23269243}.

granzyme H CRISPR/Cas9 KO Plasmid (h) - sc-416789 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H HDR Plasmid (h) - sc-416789-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H Double Nickase Plasmid (h) - sc-416789-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H Double Nickase Plasmid (h2) - sc-416789-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H CRISPR Activation Plasmid (h) - sc-416789-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H CRISPR Activation Plasmid (h2) - sc-416789-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H Lentiviral Activation Particles (h) - sc-416789-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H Lentiviral Activation Particles (h2) - sc-416789-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme H siRNA (h) - sc-60757 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

granzyme H shRNA Plasmid (h) - sc-60757-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

granzyme H shRNA (h) Lentiviral Particles - sc-60757-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU104561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9828 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9828 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GZMH siRNA (Human) - CRH2034 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Granzyme H RNAi - H00002999-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GZMH - MBS8210873 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GZMH (NM_033423.4) - SHH309690 from Creative biogene

Category siRNA
Species Reactivities Human

GZMH shRNA Plasmid (Human) - CHH2034 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GZMH miRNA 3'UTR clone - MiUTR3H-00374 from Creative biogene

Species Reactivities Human
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