FAM20B

Gene Symbol	FAM20B
Entrez Gene	9917
Alt Symbol	gxk1
Species	Human
Gene Type	protein-coding
Description	family with sequence similarity 20, member B
Other Description	glycosaminoglycan xylosylkinase|xylose kinase
Swissprots	Q5W0C3 Q5W0C4 O75063
Accessions	EAW91034 EAW91035 EAW91036 O75063 AB007944 BAA32320 AB480690 BAH79819 AK289989 BAF82678 BC046441 AAH46441 BC051794 AAH51794 CA844342 XM_011510224 XP_011508526 XM_011510225 XP_011508527 XM_011510226 XP_011508528 NM_014864 NP_055679
Function	Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG- protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1- O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized. {ECO:0000269|PubMed:19473117, ECO:0000269|PubMed:24425863}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:19473117}; Single-pass type II membrane protein {ECO:0000269|PubMed:19473117}.
Tissue Specificity	Widely expressed. Strongly expressed in pancreas, spleen and fetal liver. {ECO:0000269|PubMed:15676076, ECO:0000269|PubMed:24425863}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FAM20B full length protein - ab160713 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human FAM20B Protein - H00009917-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human FAM20B, CF - 8427-FM-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Asn27-Leu409, with an N-terminal HA tag

FAM20B protein - orb171621 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

FAM20B - H00009917-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

FAM20B fusion protein - Ag5912 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FAM20B fusion protein - Ag5680 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human FAM20B, His-tagged - FAM20B-12694H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human FAM20B, Fc-tagged - FAM20B-280H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human FAM20B, HA-tagged - FAM20B-1024H from Creative Biomart Category Protein Source CHO Cells Species Human

Human FAM20B / Gxk1 Protein (Fc Tag) - 15465-H01H-20 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Human Glycosaminoglycan xylosylkinase(FAM20B) - CSB-YP008173HU CSB-EP008173HU CSB-BP008173HU CSB-MP008173HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human FAM20B Protein, CF - 8427-FM from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Asn27-Leu409, with an N-terminal HA tag Species Human

Recombinant Human FAM20B / Gxk1 Protein (Fc tag) - PKSH030547 from Elabscience Category Protein Source Human Cells Species Human

Recombinant Human FAM20B Protein, Fc-tagged - FAM20B-686H from Creative Biomart Category Protein Source HEK293 Species Human

FAM20B Recombinant Protein Antigen - NBP1-81506PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAM20B Peptide, Human - M34GP05381H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human FAM20B / Gxk1 Protein (Fc Tag) - 15465-H01H from ABclonal Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

FAM20B / Gxk1, Recombinant Protein - MBS2545237 from MyBioSource Category Protein Prices $375.00, $905.00 Sizes 20 µg, 100 µg Source Human Cells

Glycosaminoglycan xylosylkinase, Recombinant Protein - MBS7042714 from MyBioSource Category Protein Prices $1,215.00, $2,200.00, $3,410.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Glycosaminoglycan xylosylkinase (FAM20B), Recombinant Protein - MBS1061277 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human FAM20B Protein, CF - 8427-FM from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

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