FAM20B

Gene Symbol FAM20B
Entrez Gene 9917
Alt Symbol gxk1
Species Human
Gene Type protein-coding
Description family with sequence similarity 20, member B
Other Description glycosaminoglycan xylosylkinase|xylose kinase
Swissprots Q5W0C3 Q5W0C4 O75063
Accessions EAW91034 EAW91035 EAW91036 O75063 AB007944 BAA32320 AB480690 BAH79819 AK289989 BAF82678 BC046441 AAH46441 BC051794 AAH51794 CA844342 XM_011510224 XP_011508526 XM_011510225 XP_011508527 XM_011510226 XP_011508528 NM_014864 NP_055679
Function Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG- protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1- O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized. {ECO:0000269|PubMed:19473117, ECO:0000269|PubMed:24425863}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:19473117}; Single-pass type II membrane protein {ECO:0000269|PubMed:19473117}.
Tissue Specificity Widely expressed. Strongly expressed in pancreas, spleen and fetal liver. {ECO:0000269|PubMed:15676076, ECO:0000269|PubMed:24425863}.

FAM20B CRISPR/Cas9 KO Plasmid (h) - sc-411386 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B HDR Plasmid (h) - sc-411386-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B Double Nickase Plasmid (h) - sc-411386-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B Double Nickase Plasmid (h2) - sc-411386-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B CRISPR Activation Plasmid (h) - sc-411386-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B CRISPR Activation Plasmid (h2) - sc-411386-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B Lentiviral Activation Particles (h) - sc-411386-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B Lentiviral Activation Particles (h2) - sc-411386-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM20B siRNA (h) - sc-78870 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM20B shRNA Plasmid (h) - sc-78870-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM20B shRNA (h) Lentiviral Particles - sc-78870-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU143781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8293 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8293 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FAM20B siRNA (Human) - CRH6662 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAM20B - MBS8232602 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FAM20B (NM_014864.3) - SHH290793 from Creative biogene

Category siRNA
Species Reactivities Human

FAM20B shRNA Plasmid (Human) - CHH6662 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FAM20B miRNA 3'UTR clone - MiUTR4H-TG03258 from Creative biogene

Species Reactivities Human
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