VANGL2

Gene Symbol	VANGL2
Entrez Gene	57216
Alt Symbol	LPP1, LTAP, STB1, STBM, STBM1
Species	Human
Gene Type	protein-coding
Description	VANGL planar cell polarity protein 2
Other Description	loop-tail protein 1 homolog|loop-tail-associated protein|strabismus 1|van Gogh-like protein 2|vang-like 2 (van gogh, Drosophila)|vang-like protein 2
Swissprots	Q5T212 D3DVE9 Q9ULK5
Accessions	EAW52717 EAW52718 Q9ULK5 AB033041 BAA86529 AK290981 BAF83670 AL137558 BC103920 BC166628 AAI66628 BG059541 BU162175 BX420618 XM_005245357 XP_005245414 XM_011509804 XP_011508106 XM_011509805 XP_011508107 NM_020335 NP_065068
Function	Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). {ECO:0000250|UniProtKB:Q91ZD4}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human VANGL2 full length protein - ab132660 from Abcam Category Protein Source Wheat germ Species Human

Human VANGL2 peptide - ab86632 from Abcam Category Peptide

VANGL2 / LTAP Antibody Blocking Peptide - LS-E26265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Vang-like Protein 2/VANGL2 Protein - H00057216-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

VANGL2 blocking peptide - GTX48550-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Zebrafish, Bovine

VANGL2 Peptide - AC21-1097-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Vang-like protein 2 (VANGL2) - H00057216-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Vang-like protein 2 (VANGL2) - H00057216-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

VANGL2 Peptide - 46-567P from ProSci Category Peptide Species Human, Mouse

VANGL2 fusion protein - Ag16980 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

VANGL2 fusion protein - Ag15833 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human VANGL2, His-tagged - VANGL2-3644H from Creative Biomart Category Protein Source E.coli Species Human

VANGL2 Protein - abx164474 from Abbexa Category Protein Species Human, Mouse, Rat

VANGL2, Peptide - MBS426143 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Bovine, Zebrafish

Vang-like Protein 2/VANGL2 Recombinant Protein Antigen - NBP1-81428PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

VANGL2-Blocking-Peptide-N-term - BP20148a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VANGL2-Blocking-Peptide-C-Term - BP21414b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VANGL2 Peptide, Human - M34GP17233H from Creative Peptides Category Peptide Source Synthetic. Species Human

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