VANGL2

Gene Symbol VANGL2
Entrez Gene 57216
Alt Symbol LPP1, LTAP, STB1, STBM, STBM1
Species Human
Gene Type protein-coding
Description VANGL planar cell polarity protein 2
Other Description loop-tail protein 1 homolog|loop-tail-associated protein|strabismus 1|van Gogh-like protein 2|vang-like 2 (van gogh, Drosophila)|vang-like protein 2
Swissprots Q5T212 D3DVE9 Q9ULK5
Accessions EAW52717 EAW52718 Q9ULK5 AB033041 BAA86529 AK290981 BAF83670 AL137558 BC103920 BC166628 AAI66628 BG059541 BU162175 BX420618 XM_005245357 XP_005245414 XM_011509804 XP_011508106 XM_011509805 XP_011508107 NM_020335 NP_065068
Function Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). {ECO:0000250|UniProtKB:Q91ZD4}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Wnt signaling pathway

Vangl2 CRISPR/Cas9 KO Plasmid (h) - sc-400805 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 HDR Plasmid (h) - sc-400805-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 Double Nickase Plasmid (h) - sc-400805-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 Double Nickase Plasmid (h2) - sc-400805-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 CRISPR Activation Plasmid (h) - sc-400805-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 CRISPR Activation Plasmid (h2) - sc-400805-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 Lentiviral Activation Particles (h) - sc-400805-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 Lentiviral Activation Particles (h2) - sc-400805-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Vangl2 siRNA (h) - sc-45595 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Vangl2 shRNA Plasmid (h) - sc-45595-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Vangl2 shRNA (h) Lentiviral Particles - sc-45595-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU010511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22637 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22637 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

VANGL2 siRNA (Human) - CRJ1401 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VANGL2 - MBS8220883 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human VANGL2 (NM_020335.2) - SHH442224 from Creative biogene

Category siRNA
Species Reactivities Human

VANGL2 shRNA Plasmid (Human) - CHJ1401 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

VANGL2 miRNA 3'UTR clone - MiUTR4H-TG09743 from Creative biogene

Species Reactivities Human
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