LPL

Gene Symbol	LPL
Entrez Gene	4023
Alt Symbol	HDLCQ11, LIPD
Species	Human
Gene Type	protein-coding
Description	lipoprotein lipase
Other Description	-
Swissprots	B2R5T9 P06858 Q96FC4 Q16282 Q16283
Accessions	AAA59528 AAB20999 AAB21000 AAC61679 AAM23256 AAY85371 CAA48230 EAW63764 P06858 AK092286 BAG52519 AK222464 BAD96184 AK290290 BAF82979 AK297164 BAH12512 AK312311 BAG35236 BC011353 AAH11353 BT006726 AAP35372 CR457054 CAG33335 DA485210 DQ893541 ABM84467 DQ893751 ABM84677 M15856 AAB59536 M26380 S78266 X14390 CAA32564 X54516 CAA38372 NM_000237 NP_000228
Function	The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Secreted {ECO:0000250}. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). {ECO:0000250}.
Top Pathways	Alzheimer's disease, PPAR signaling pathway, Glycerolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Lipoprotein lipase (mutated N318 S) full length protein - ab125807 from Abcam Category Protein Source HEK 293 cells Species Human

Human Lipoprotein lipase full length protein - ab115504 from Abcam Category Protein Source HEK 293 cells Species Human

Human Lipoprotein lipase full length protein - ab115500 from Abcam Category Protein Source E. coli Species Human

LPL / Lipoprotein Lipase Blocking Peptide - LS-E3038 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LPL / Lipoprotein Lipase Antibody Blocking Peptide - LS-E22062 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Lipoprotein Lipase/LPL Protein - H00004023-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

LPL-Antibody-Center-Blocking-Peptide - BP14170c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human LPL protein - orb168745 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human LPL protein - orb168744 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

LPL Blocking Peptide - 33R-5003 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LPL Blocking Peptide - 33R-11019 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Lipoprotein lipase - H00004023-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Lipoprotein Lipase, Human Recombinant - 228-12238-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Lipoprotein Lipase Human - 228-12238-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Lipoprotein Lipase Human - 228-12238-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

Lipoprotein Lipase, Human Recombinant, HEK - 228-12239-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source HEK293 (Human Embryonic Kidney cell line). Species Human

LPL fusion protein - Ag10450 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

LPL fusion protein - ag10431 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

LPL Human - ENPS-093 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

LPL Human, HEK - ENPS-094 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source HEK293 (Human Embryonic Kidney cell line). Species Human

Recombinant Human Lipoprotein Lipase - BP000651-ENZ-086 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human Lipoprotein Lipase, HEK - BP000651-ENZ-087 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source HEK293 (Human Embryonic Kidney cell line)-derived. Species Human

LPL Human Protein - GWB-BSP229 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human LPL, Flag-tagged - LPL-1015H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human LPL, His-tagged - LPL-1014H from Creative Biomart Category Protein Source E. coli Species Human

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