LPL

Gene Symbol LPL
Entrez Gene 4023
Alt Symbol HDLCQ11, LIPD
Species Human
Gene Type protein-coding
Description lipoprotein lipase
Other Description -
Swissprots B2R5T9 P06858 Q96FC4 Q16282 Q16283
Accessions AAA59528 AAB20999 AAB21000 AAC61679 AAM23256 AAY85371 CAA48230 EAW63764 P06858 AK092286 BAG52519 AK222464 BAD96184 AK290290 BAF82979 AK297164 BAH12512 AK312311 BAG35236 BC011353 AAH11353 BT006726 AAP35372 CR457054 CAG33335 DA485210 DQ893541 ABM84467 DQ893751 ABM84677 M15856 AAB59536 M26380 S78266 X14390 CAA32564 X54516 CAA38372 NM_000237 NP_000228
Function The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Secreted {ECO:0000250}. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). {ECO:0000250}.
Top Pathways Alzheimer's disease, PPAR signaling pathway, Glycerolipid metabolism

LPL CRISPR/Cas9 KO Plasmid (h) - sc-400751 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL HDR Plasmid (h) - sc-400751-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL Double Nickase Plasmid (h) - sc-400751-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL Double Nickase Plasmid (h2) - sc-400751-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL CRISPR Activation Plasmid (h) - sc-400751-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL CRISPR Activation Plasmid (h2) - sc-400751-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL Lentiviral Activation Particles (h) - sc-400751-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL Lentiviral Activation Particles (h2) - sc-400751-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPL siRNA (h) - sc-44900 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPL shRNA Plasmid (h) - sc-44900-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPL shRNA (h) Lentiviral Particles - sc-44900-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lipoprotein Lipase/LPL RNAi - H00004023-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU012071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1660 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1660 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11059 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11059

LPL siRNA (Human) - CRH2722 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LPL (NM_000237.2) - SHH333607 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LPL(NM_000237.2) - SHH160013 from Creative biogene

Category siRNA
Species Reactivities Human

LPL shRNA Plasmid (Human) - CHH2722 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LPL miRNA 3'UTR clone - MiUTR1H-05885 from Creative biogene

Species Reactivities Human
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