| Gene Symbol | CHKA |
|---|---|
| Entrez Gene | 1119 |
| Alt Symbol | CHK, CK, CKI, EK |
| Species | Human |
| Gene Type | protein-coding |
| Description | choline kinase alpha |
| Other Description | CHETK-alpha|ethanolamine kinase |
| Swissprots | P35790 Q8NE29 |
| Accessions | EAW74694 EAW74695 EAW74696 P35790 AI809679 AK054792 AK092643 AL834403 BC036471 AAH36471 BE260889 BG703955 BG723115 BI195927 BU617910 D10704 BAA01547 XR_428904 XR_428905 XR_949772 XR_949773 XR_949774 XR_949775 XR_949776 XR_949777 NM_001277 NP_001268 NM_212469 NP_997634 |
| Function | Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. {ECO:0000269|PubMed:19915674}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Choline metabolism in cancer, Glycerophospholipid metabolism |