Gene Symbol | CHKA |
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Entrez Gene | 1119 |
Alt Symbol | CHK, CK, CKI, EK |
Species | Human |
Gene Type | protein-coding |
Description | choline kinase alpha |
Other Description | CHETK-alpha|ethanolamine kinase |
Swissprots | P35790 Q8NE29 |
Accessions | EAW74694 EAW74695 EAW74696 P35790 AI809679 AK054792 AK092643 AL834403 BC036471 AAH36471 BE260889 BG703955 BG723115 BI195927 BU617910 D10704 BAA01547 XR_428904 XR_428905 XR_949772 XR_949773 XR_949774 XR_949775 XR_949776 XR_949777 NM_001277 NP_001268 NM_212469 NP_997634 |
Function | Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. {ECO:0000269|PubMed:19915674}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Choline metabolism in cancer, Glycerophospholipid metabolism |
Human Choline kinase alpha full length protein - ab114521 from Abcam
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Human Choline kinase alpha peptide - ab98290 from Abcam
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Human Choline kinase alpha protein fragment - ab152275 from Abcam
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CHKA / CK / Choline Kinase Antibody Blocking Peptide - LS-E8652 from LifeSpan Bioscience
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CHKA / CK / Choline Kinase Antibody Blocking Peptide - LS-E9558 from LifeSpan Bioscience
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Recombinant Human Choline kinase alpha Protein - H00001119-Q01 from Novus Biologicals
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Recombinant Human Choline kinase alpha Protein - H00001119-P01 from Novus Biologicals
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Choline kinase alpha Peptide - P2169 from Novus Biologicals
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Choline kinase alpha Peptide - P3228 from Novus Biologicals
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CHK-Antibody-N-term-Blocking-Peptide - BP7064a from Abgent, a WuXi AppTec company
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Choline-kinase-alpha-CHK-Antibody-C-term-Blocking-peptide - BP8179b from Abgent, a WuXi AppTec company
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CHKA Blocking Peptide - 33R-4929 from Fitzgerald
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Choline kinase alpha - H00001119-P01-10 from Acris Antibodies
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Choline kinase alpha - H00001119-P01-25 from Acris Antibodies
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Choline kinase alpha - H00001119-Q01-10 from Acris Antibodies
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Choline kinase alpha - H00001119-Q01-25 from Acris Antibodies
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Choline kinase alpha - P6188 from Acris Antibodies
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Choline kinase alpha - P6189 from Acris Antibodies
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CHKA fusion protein - ag4761 from Proteintech Group
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CHKA fusion protein - ag4997 from Proteintech Group
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Recombinant Human CHKA - CHKA-26903TH from Creative Biomart
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Recombinant Human CHKA, MYC/DDK-tagged - CHKA-65H from Creative Biomart
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Recombinant Human Choline kinase alpha(CHKA) - CSB-YP005353HU CSB-EP005353HU CSB-BP005353HU CSB-MP005353HU from Cusabio
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CHKA Peptide - abx165035 from Abbexa
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Choline kinase alpha (transcript variant 2) - TP307209 from Acris Antibodies
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