Gene Symbol | CHKA |
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Entrez Gene | 1119 |
Alt Symbol | CHK, CK, CKI, EK |
Species | Human |
Gene Type | protein-coding |
Description | choline kinase alpha |
Other Description | CHETK-alpha|ethanolamine kinase |
Swissprots | P35790 Q8NE29 |
Accessions | EAW74694 EAW74695 EAW74696 P35790 AI809679 AK054792 AK092643 AL834403 BC036471 AAH36471 BE260889 BG703955 BG723115 BI195927 BU617910 D10704 BAA01547 XR_428904 XR_428905 XR_949772 XR_949773 XR_949774 XR_949775 XR_949776 XR_949777 NM_001277 NP_001268 NM_212469 NP_997634 |
Function | Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. {ECO:0000269|PubMed:19915674}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Choline metabolism in cancer, Glycerophospholipid metabolism |
CHKA 293T Cell Transient Overexpression Lysate(Denatured) - H00001119-T01 from Acris Antibodies
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CHKA overexpression lysate - LY400512 from Acris Antibodies
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CHKA overexpression lysate - LY403943 from Acris Antibodies
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CHKA 293 Cell Lysate - 400517 from ABBIOTEC
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Choline kinase alpha Overexpression Lysate (Denatured) - H00001119-T01 from Novus Biologicals
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Choline kinase alpha Overexpression Lysate (Native) - NBL1-09157 from Novus Biologicals
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CHKA Over-expression Lysate Product - GWB-794316 from Genway Biotech
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Choline kinase alpha Overexpression Lysate (Native) - NBP2-04484 from Novus Biologicals
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Panoply™ Human CHKA Knockdown Stable Cell Line - CSC-DC003095 from Creative biogene
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