Gene Symbol | CBFB |
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Entrez Gene | 865 |
Alt Symbol | PEBP2B |
Species | Human |
Gene Type | protein-coding |
Description | core-binding factor, beta subunit |
Other Description | CBF-beta|PEA2-beta|PEBP2-beta|SL3-3 enhancer factor 1 beta subunit|SL3-3 enhancer factor 1 subunit beta|SL3/AKV core-binding factor beta subunit|core-binding factor subunit beta|polyomavirus enhancer binding protein 2, beta subunit|polyomavirus enhancer-binding protein 2 beta subunit |
Swissprots | Q9HCT2 A8K347 Q13951 Q13124 |
Accessions | EAW83066 EAW83067 EAW83068 EAW83069 EAW83070 EAW83071 Q13951 AA020956 AF294326 AAG01553 AK290462 BAF83151 AK291834 BAF84523 AK311084 AK311724 BC018509 AAH18509 BM679848 BT006862 AAP35508 DQ890558 ABM92175 DQ893719 ABM84645 L20298 AAA02868 XM_005256212 XP_005256269 XM_006721321 XP_006721384 NM_001755 NP_001746 NM_022845 NP_074036 |
Function | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM- CSF promoters. CBFB enhances DNA binding by RUNX1. |
Subcellular Location | Nucleus {ECO:0000305}. |
CBFβ Antibody - 12902 from Cell Signaling Technology
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PEBP2β (FL-182) - sc-20693 from Santa Cruz Biotechnology
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PEBP2β (H-10) - sc-166126 from Santa Cruz Biotechnology
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PEBP2β (141,4,1) - sc-56751 from Santa Cruz Biotechnology
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PEBP2β (E-20) - sc-17181 from Santa Cruz Biotechnology
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PEBP2β (A-4) - sc-166142 from Santa Cruz Biotechnology
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Anti-CBFb antibody - ab33516 from Abcam
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Anti-CBFb antibody - ab72696 from Abcam
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Anti-CBFb antibody - ab169979 from Abcam
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Anti-CBFb antibody - ab167382 from Abcam
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Anti-CBFb antibody [EPR6321] - ab124693 from Abcam
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Anti-CBFb antibody [EPR6322] - ab133600 from Abcam
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Anti-CBFB Antibody (Internal, clone EPR6321) - LS-C138784 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, clone EPR6322) - LS-C139002 from LifeSpan Bioscience
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Anti-CBFB Antibody (aa2-165) - LS-C150105 from LifeSpan Bioscience
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Anti-CBFB Antibody (N-Terminus) - LS-C169494 from LifeSpan Bioscience
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Anti-CBFB Antibody (N-Terminus) IHC-plus™ - LS-B8269 from LifeSpan Bioscience
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Anti-CBFB Antibody (aa11-60) IHC-plus⢠- LS-B7059 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, AP) - LS-C206475 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, APC) - LS-C206476 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, Biotin) - LS-C206477 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, FITC) - LS-C206478 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, Azide-free, HRP) - LS-C207953 from LifeSpan Bioscience
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Anti-CBFB Antibody (Internal, PE) - LS-C206480 from LifeSpan Bioscience
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Anti-CBFB Antibody (aa166-182) - LS-C290215 from LifeSpan Bioscience
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