Gene Symbol | CBFB |
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Entrez Gene | 865 |
Alt Symbol | PEBP2B |
Species | Human |
Gene Type | protein-coding |
Description | core-binding factor, beta subunit |
Other Description | CBF-beta|PEA2-beta|PEBP2-beta|SL3-3 enhancer factor 1 beta subunit|SL3-3 enhancer factor 1 subunit beta|SL3/AKV core-binding factor beta subunit|core-binding factor subunit beta|polyomavirus enhancer binding protein 2, beta subunit|polyomavirus enhancer-binding protein 2 beta subunit |
Swissprots | Q9HCT2 A8K347 Q13951 Q13124 |
Accessions | EAW83066 EAW83067 EAW83068 EAW83069 EAW83070 EAW83071 Q13951 AA020956 AF294326 AAG01553 AK290462 BAF83151 AK291834 BAF84523 AK311084 AK311724 BC018509 AAH18509 BM679848 BT006862 AAP35508 DQ890558 ABM92175 DQ893719 ABM84645 L20298 AAA02868 XM_005256212 XP_005256269 XM_006721321 XP_006721384 NM_001755 NP_001746 NM_022845 NP_074036 |
Function | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM- CSF promoters. CBFB enhances DNA binding by RUNX1. |
Subcellular Location | Nucleus {ECO:0000305}. |
PEBP2β siRNA (h) - sc-37681 from Santa Cruz Biotechnology
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PEBP2β shRNA Plasmid (h) - sc-37681-SH from Santa Cruz Biotechnology
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PEBP2β shRNA (h) Lentiviral Particles - sc-37681-V from Santa Cruz Biotechnology
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CBFB RNAi - H00000865-R01 from Novus Biologicals
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MISSION® esiRNA - EHU121261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5408 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5408 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11168 from Sigma-Aldrich
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CBFB siRNA (Human) - CRH0610 from Cohesion Biosciences
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CBFB RNAi - H00000865-R02 from Novus Biologicals
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CBFB - MBS8213217 from MyBioSource
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shRNA set against Human CBFB (NM_001755.2) - SHH255289 from Creative biogene
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shRNA set against Human CBFB(NM_001755.2) - SHG144235 from Creative biogene
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shRNA set against Human CBFB(NM_022845.2) - SHG144253 from Creative biogene
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Human CBFB siRNA - orb261112 from Biorbyt
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CBFB shRNA Plasmid (Human) - CHH0610 from Cohesion Biosciences
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CBFB miRNA 3'UTR clone - MiUTR1H-01702 from Creative biogene
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CBFB miRNA 3'UTR clone - MiUTR1H-01703 from Creative biogene
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