| Gene Symbol |
CBFB
|
| Entrez Gene |
865
|
| Alt Symbol |
PEBP2B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
core-binding factor, beta subunit
|
| Other Description |
CBF-beta|PEA2-beta|PEBP2-beta|SL3-3 enhancer factor 1 beta subunit|SL3-3 enhancer factor 1 subunit beta|SL3/AKV core-binding factor beta subunit|core-binding factor subunit beta|polyomavirus enhancer binding protein 2, beta subunit|polyomavirus enhancer-binding protein 2 beta subunit
|
| Swissprots |
Q9HCT2 A8K347 Q13951 Q13124
|
| Accessions |
EAW83066 EAW83067 EAW83068 EAW83069 EAW83070 EAW83071 Q13951 AA020956 AF294326 AAG01553 AK290462 BAF83151 AK291834 BAF84523 AK311084 AK311724 BC018509 AAH18509 BM679848 BT006862 AAP35508 DQ890558 ABM92175 DQ893719 ABM84645 L20298 AAA02868 XM_005256212 XP_005256269 XM_006721321 XP_006721384 NM_001755 NP_001746 NM_022845 NP_074036
|
| Function |
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM- CSF promoters. CBFB enhances DNA binding by RUNX1.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|